1 GAF#1
244-363 aa · 120 aa · 20.4% of protein
Raw token
GAF:244:0.00000137:363:128:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0345_RS14510
Histidine kinase, Classic
Enterococcus faecalis ATCC 29200 · GCF_000159655
ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000159655#HMPREF0345_RS14510Stable P2CS identifier used across views.
GenomeGCF_000159655Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 589 aa (51.6%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
Domain-by-domain annotation3 items
2 His_kinase#2
378-456 aa · 79 aa · 13.4% of protein
Raw token
His_kinase:378:3.34e-30:456:80:803 HATPase_c#3
476-580 aa · 105 aa · 17.8% of protein
Raw token
HATPase_c:476:0.00000000000105:580:109:109- Raw architecture: GAF:244:0.00000137:363:128:133#His_kinase:378:3.34e-30:456:80:80#HATPase_c:476:0.00000000000105:580:109:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000159655::NZ_GG668757.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span81470-83948Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0345_0163RefSeq proteinWP_002380990.1
Context group ID
GCF_000159655::NZ_GG668757.1::G00003Context members
HMPREF0345_RS14510HMPREF0345_RS14515
Partner locus tags
HMPREF0345_RS14510HMPREF0345_RS14515
Partner old locus tags
HMPREF0345_0163HMPREF0345_0164
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002380990.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP6V730Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP6V730_ENTFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0345_RS14510Primary locus identifier stored in the genes table.
Old locus tagHMPREF0345_0163Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG668757.1Sequence record reported by the local genomic context database.
Genomic interval81 470-83 239 nt1 770 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span81 470-83 948 ntGCF_000159655::NZ_GG668757.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000159655::NZ_GG668757.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG668757.1All displayed genes belong to this local TCS context.
Neighborhood span81 470-83 948 nt2 479 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
81 470 nt83 948 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0345_RS14510GCF_000159655#HMPREF0345_RS14510
HKClassicCurrent focus
81 470-83 239 nt · Forward (+)
HMPREF0345_RS14515GCF_000159655#HMPREF0345_RS14515
RRLytTR
83 220-83 948 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147255#HMPREF9511_RS05215Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1114759
Simplified PFAM architecture for HKOC_1114759
PFAM domain coverage: 364 / 589 aa (61.8%)
1 aa589 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[26-206] | His_kinase[378-456] | HATPase_c[476-579]
- Domain count: 3
- Matched identifier: HKOC_1114759
- Positioned domains: 5TM-5TMR_LYT 26-206 ; His_kinase 378-456 ; HATPase_c 476-579
Cluster members and taxonomy
Representative gene: GCF_000147255#HMPREF9511_RS05215
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 525 271 · GCF_000159655
AssemblyASM15965v1 · Scaffoldhaploid
Genome composition2 973 369 bp · 37,5% GCEnterococcus faecalis ATCC 29200
Signal transduction countsGenes 26 · HK 12 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key