1 HAMP#1
171-241 aa · 71 aa · 15.3% of protein
Raw token
HAMP:171:0.0000000287:241:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFRG_RS17075
Histidine kinase, Classic
Enterococcus faecium 1,231,501 · GCF_000157555
ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157555#EFRG_RS17075Stable P2CS identifier used across views.
GenomeGCF_000157555Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 464 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa464 aa
Domain-by-domain annotation3 items
2 HisKA#2
246-308 aa · 63 aa · 13.6% of protein
Raw token
HisKA:246:0.00000000000811:308:63:643 HATPase_c#3
353-464 aa · 112 aa · 24.1% of protein
Raw token
HATPase_c:353:1.13e-32:464:112:109- Raw architecture: HAMP:171:0.0000000287:241:71:69#HisKA:246:0.00000000000811:308:63:64#HATPase_c:353:1.13e-32:464:112:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000157555::NZ_GG688440.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span172874-174948Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFRG_02299RefSeq proteinWP_002307657.1
Context group ID
GCF_000157555::NZ_GG688440.1::G00005Context members
EFRG_RS17070EFRG_RS17075
Partner locus tags
EFRG_RS17070EFRG_RS17075
Partner old locus tags
EFRG_02298EFRG_02299
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002307657.1Primary protein accession used for annex mappings.
UniProt accessionA0A7W1XIB2Primary UniProt accession resolved in the annex database.
UniProt IDA0A7W1XIB2_9ENTEDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFRG_RS17075Primary locus identifier stored in the genes table.
Old locus tagEFRG_02299Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688440.1Sequence record reported by the local genomic context database.
Genomic interval173 554-174 948 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span172 874-174 948 ntGCF_000157555::NZ_GG688440.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000157555::NZ_GG688440.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688440.1All displayed genes belong to this local TCS context.
Neighborhood span172 874-174 948 nt2 075 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
172 874 nt174 948 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFRG_RS17070GCF_000157555#EFRG_RS17070
RROmpR
172 874-173 554 nt · Forward (+)
EFRG_RS17075GCF_000157555#EFRG_RS17075
HKClassicCurrent focus
173 554-174 948 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157555#EFRG_RS17075The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783734
Simplified PFAM architecture for HKOC_1783734
PFAM domain coverage: 173 / 464 aa (37.3%)
1 aa464 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[246-308] | HATPase_c[354-463]
- Domain count: 2
- Matched identifier: HKOC_1783734
- Positioned domains: HisKA 246-308 ; HATPase_c 354-463
Cluster members and taxonomy
Representative gene: GCF_000157555#EFRG_RS17075
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 565 658 · GCF_000157555
AssemblyASM15755v1 · Scaffoldhaploid
Genome composition2 871 230 bp · 38,0% GCEnterococcus faecium 1,231,501
Signal transduction countsGenes 41 · HK 19 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key