1 His_kinase#1
375-454 aa · 80 aa · 13.9% of protein
Raw token
His_kinase:375:4.12e-27:454:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFRG_RS09485
Histidine kinase, Classic
Enterococcus faecium 1,231,501 · GCF_000157555
ClassHKTypeClassicLength575 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000157555#EFRG_RS09485Stable P2CS identifier used across views.
GenomeGCF_000157555Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length575 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 575 aa (30.4%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa575 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
474-568 aa · 95 aa · 16.5% of protein
Raw token
HATPase_c:474:0.0000000000703:568:105:109- Raw architecture: His_kinase:375:4.12e-27:454:80:80#HATPase_c:474:0.0000000000703:568:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000157555::NZ_GG688436.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span758070-759797Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFRG_00739RefSeq proteinWP_002306534.1
Context group ID
GCF_000157555::NZ_GG688436.1::G00019Context members
EFRG_RS09485
Partner locus tags
EFRG_RS09485
Partner old locus tags
EFRG_00739
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002306534.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFRG_RS09485Primary locus identifier stored in the genes table.
Old locus tagEFRG_00739Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688436.1Sequence record reported by the local genomic context database.
Genomic interval758 070-759 797 nt1 728 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span758 070-759 797 ntGCF_000157555::NZ_GG688436.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000157555::NZ_GG688436.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688436.1All displayed genes belong to this local TCS context.
Neighborhood span758 070-759 797 nt1 728 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
758 070 nt759 797 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EFRG_RS09485GCF_000157555#EFRG_RS09485
HKClassicCurrent focus
758 070-759 797 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157555#EFRG_RS09485The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1188205
Simplified PFAM architecture for HKOC_1188205
PFAM domain coverage: 175 / 575 aa (30.4%)
1 aa575 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[376-454] | HATPase_c[473-568]
- Domain count: 2
- Matched identifier: HKOC_1188205
- Positioned domains: His_kinase 376-454 ; HATPase_c 473-568
Cluster members and taxonomy
Representative gene: GCF_000157555#EFRG_RS09485
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 565 658 · GCF_000157555
AssemblyASM15755v1 · Scaffoldhaploid
Genome composition2 871 230 bp · 38,0% GCEnterococcus faecium 1,231,501
Signal transduction countsGenes 41 · HK 19 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key