Gene detail

EFQG_RS13310

Histidine kinase, Classic

Enterococcus faecium 1,231,502 · GCF_000157535

ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157535#EFQG_RS13310Stable P2CS identifier used across views.
GenomeGCF_000157535Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1000690Run 6 · 2171 sequences · id 100% · cov 80% · representative
External referencesWP_002294131.1 · A0AAV3GUQ9 · MIST4 EFQG_RS13310RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 611 aa (58.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
HAMP: 182-251 aa (70 aa)1PAS: 261-368 aa (108 aa)2HisKA: 377-444 aa (68 aa)3HATPase_c: 493-604 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
182-251 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:182:4.57e-18:251:70:69
2 PAS#2
261-368 aa · 108 aa · 17.7% of protein
Raw tokenPAS:261:0.00000000226:368:113:113
3 HisKA#3
377-444 aa · 68 aa · 11.1% of protein
Raw tokenHisKA:377:1.03e-18:444:68:64
4 HATPase_c#4
493-604 aa · 112 aa · 18.3% of protein
Raw tokenHATPase_c:493:1e-31:604:112:109
  • Raw architecture: HAMP:182:4.57e-18:251:70:69#PAS:261:0.00000000226:368:113:113#HisKA:377:1.03e-18:444:68:64#HATPase_c:493:1e-31:604:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000157535::NZ_GG688489.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span119816-122360Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFQG_01364RefSeq proteinWP_002294131.1
Context group IDGCF_000157535::NZ_GG688489.1::G00015
Context members
EFQG_RS13305EFQG_RS13310
Partner locus tags
EFQG_RS13305EFQG_RS13310
Partner old locus tags
EFQG_01363EFQG_01364
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002294131.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GUQ9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GUQ9_ENTFCDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFQG_RS13310Primary locus identifier stored in the genes table.
Old locus tagEFQG_01364Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688489.1Sequence record reported by the local genomic context database.
Genomic interval120 525-122 360 nt1 836 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span119 816-122 360 ntGCF_000157535::NZ_GG688489.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157535::NZ_GG688489.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688489.1All displayed genes belong to this local TCS context.
Neighborhood span119 816-122 360 nt2 545 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 816 nt122 360 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFQG_RS13305GCF_000157535#EFQG_RS13305
RROmpR

119 816-120 520 nt · Forward (+)

Old locus EFQG_01363RefSeq WP_002288850.1
EFQG_RS13310GCF_000157535#EFQG_RS13310
HKClassicCurrent focus

120 525-122 360 nt · Forward (+)

Old locus EFQG_01364RefSeq WP_002294131.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1000690Run 6 · HK · 2171 sequences
Representative sequenceGCF_000157535#EFQG_RS13310The current gene is the representative for this cluster.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1000690

Simplified PFAM architecture for HKOC_1000690

PFAM domain coverage: 381 / 611 aa (62.4%)

1 aa611 aa
Cache_WalK: 79-166 aaCache_WalKHAMP: 199-251 aaHAMPPAS: 262-323 aaPASHisKA: 378-444 aaHisKAHATPase_c: 493-603 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-166] | HAMP[199-251] | PAS[262-323] | HisKA[378-444] | HATPase_c[493-603]
  • Domain count: 5
  • Matched identifier: HKOC_1000690
  • Positioned domains: Cache_WalK 79-166 ; HAMP 199-251 ; PAS 262-323 ; HisKA 378-444 ; HATPase_c 493-603
Cluster members and taxonomy
Visualization

Representative gene: GCF_000157535#EFQG_RS13310

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 657 · GCF_000157535
AssemblyASM15753v1 · Scaffoldhaploid
Genome composition3 084 930 bp · 37,5% GCEnterococcus faecium 1,231,502
Signal transduction countsGenes 41 · HK 20 · RR 21CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key