Gene detail

EFLG_RS06195

Histidine kinase, Classic

Enterococcus faecalis D6 · GCF_000157455

ClassHKTypeClassicLength856 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157455#EFLG_RS06195Stable P2CS identifier used across views.
GenomeGCF_000157455Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_0471055Run 6 · 614 sequences · id 100% · cov 80%
External referencesWP_002382887.1 · A0AAV3GKL9 · MIST4 EFLG_RS06195RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length856 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage499 / 856 aa (58.3%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa856 aa
KdpD: 13-221 aa (209 aa)1GAF_3: 502-619 aa (118 aa)2HisKA: 639-702 aa (64 aa)3HATPase_c: 749-856 aa (108 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
13-221 aa · 209 aa · 24.4% of protein
Raw tokenKdpD:13:7.72e-120:221:210:210
2 GAF_3#2
502-619 aa · 118 aa · 13.8% of protein
Raw tokenGAF_3:502:0.0000000953:619:127:129
3 HisKA#3
639-702 aa · 64 aa · 7.5% of protein
Raw tokenHisKA:639:0.0000000000000531:702:64:64
4 HATPase_c#4
749-856 aa · 108 aa · 12.6% of protein
Raw tokenHATPase_c:749:0.000000000000023:856:110:109
  • Raw architecture: KdpD:13:7.72e-120:221:210:210#GAF_3:502:0.0000000953:619:127:129#HisKA:639:0.0000000000000531:702:64:64#HATPase_c:749:0.000000000000023:856:110:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000157455::NZ_GG688628.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span247903-251174Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFLG_01867RefSeq proteinWP_002382887.1
Context group IDGCF_000157455::NZ_GG688628.1::G00015
Context members
EFLG_RS06195EFLG_RS06200
Partner locus tags
EFLG_RS06195EFLG_RS06200
Partner old locus tags
EFLG_01867EFLG_01868
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002382887.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GKL9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GKL9_ENTFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFLG_RS06195Primary locus identifier stored in the genes table.
Old locus tagEFLG_01867Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688628.1Sequence record reported by the local genomic context database.
Genomic interval247 903-250 473 nt2 571 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span247 903-251 174 ntGCF_000157455::NZ_GG688628.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157455::NZ_GG688628.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688628.1All displayed genes belong to this local TCS context.
Neighborhood span247 903-251 174 nt3 272 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
247 903 nt251 174 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFLG_RS06195GCF_000157455#EFLG_RS06195
HKClassicCurrent focus

247 903-250 473 nt · Forward (+)

Old locus EFLG_01867RefSeq WP_002382887.1
EFLG_RS06200GCF_000157455#EFLG_RS06200
RROmpR

250 485-251 174 nt · Forward (+)

Old locus EFLG_01868RefSeq WP_002358569.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0471055Run 6 · HK · 614 sequences
Representative sequenceGCF_032681025#RX141_RS02125Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + GAF_3 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0471055

Simplified PFAM architecture for HKOC_0471055

PFAM domain coverage: 604 / 861 aa (70.2%)

1 aa861 aa
KdpD: 13-221 aaKdpDDUF4118: 374-479 aaDUF4118GAF_3: 502-618 aaGAF_3HisKA: 639-703 aaHisKAHATPase_c: 750-856 aaHATPase_c
KdpDDUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: KdpD[13-221] | DUF4118[374-479] | GAF_3[502-618] | HisKA[639-703] | HATPase_c[750-856]
  • Domain count: 5
  • Matched identifier: HKOC_0471055
  • Positioned domains: KdpD 13-221 ; DUF4118 374-479 ; GAF_3 502-618 ; HisKA 639-703 ; HATPase_c 750-856
Cluster members and taxonomy
Visualization

Representative gene: GCF_032681025#RX141_RS02125

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 650 · GCF_000157455
AssemblyASM15745v1 · Scaffoldhaploid
Genome composition2 906 246 bp · 37,5% GCEnterococcus faecalis D6
Signal transduction countsGenes 32 · HK 15 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key