Gene detail

EFPG_RS03625

Histidine kinase, Classic

Enterococcus faecium 1,230,933 · GCF_000157435

ClassHKTypeClassicLength402 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157435#EFPG_RS03625Stable P2CS identifier used across views.
GenomeGCF_000157435Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2422855Run 6 · 3369 sequences · id 100% · cov 80%
External referencesWP_002295267.1 · Q3XYJ6 · MIST4 EFPG_RS03625RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length402 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 402 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa402 aa
HisKA: 163-230 aa (68 aa)1HATPase_c: 276-387 aa (112 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
163-230 aa · 68 aa · 16.9% of protein
Raw tokenHisKA:163:0.0000000000000439:230:68:64
2 HATPase_c#2
276-387 aa · 112 aa · 27.9% of protein
Raw tokenHATPase_c:276:6.16e-27:387:113:109
  • Raw architecture: HisKA:163:0.0000000000000439:230:68:64#HATPase_c:276:6.16e-27:387:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000157435::NZ_GG692538.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span592-2476Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFPG_00717RefSeq proteinWP_002295267.1
Context group IDGCF_000157435::NZ_GG692538.1::G00013
Context members
EFPG_RS03620EFPG_RS03625
Partner locus tags
EFPG_RS03620EFPG_RS03625
Partner old locus tags
EFPG_00716EFPG_00717
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002295267.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYJ6Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYJ6_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFPG_RS03625Primary locus identifier stored in the genes table.
Old locus tagEFPG_00717Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692538.1Sequence record reported by the local genomic context database.
Genomic interval1 268-2 476 nt1 209 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span592-2 476 ntGCF_000157435::NZ_GG692538.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157435::NZ_GG692538.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692538.1All displayed genes belong to this local TCS context.
Neighborhood span592-2 476 nt1 885 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
592 nt2 476 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFPG_RS03620GCF_000157435#EFPG_RS03620
RROmpR

592-1 281 nt · Forward (+)

Old locus EFPG_00716RefSeq WP_002295268.1
EFPG_RS03625GCF_000157435#EFPG_RS03625
HKClassicCurrent focus

1 268-2 476 nt · Forward (+)

Old locus EFPG_00717RefSeq WP_002295267.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2422855Run 6 · HK · 3369 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS12560Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2422855

Simplified PFAM architecture for HKOC_2422855

PFAM domain coverage: 177 / 402 aa (44.0%)

1 aa402 aa
HisKA: 164-229 aaHisKAHATPase_c: 276-386 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[164-229] | HATPase_c[276-386]
  • Domain count: 2
  • Matched identifier: HKOC_2422855
  • Positioned domains: HisKA 164-229 ; HATPase_c 276-386
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS12560

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 656 · GCF_000157435
AssemblyASM15743v1 · Scaffoldhaploid
Genome composition3 140 782 bp · 38,0% GCEnterococcus faecium 1,230,933
Signal transduction countsGenes 36 · HK 18 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key