Gene detail

EFDG_RS08470

Histidine kinase, Classic

Enterococcus faecalis ATCC 4200 · GCF_000157195

ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157195#EFDG_RS08470Stable P2CS identifier used across views.
GenomeGCF_000157195Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1182886Run 6 · 114 sequences · id 100% · cov 80%
External referencesWP_002395515.1 · MIST4 EFDG_RS08470RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
HAMP: 288-360 aa (73 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 464-574 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw tokenHAMP:288:0.0000000893:360:73:69
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw tokenHis_kinase:375:7.38e-28:453:80:80
3 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw tokenHATPase_c:464:0.0000000000221:574:113:109
  • Raw architecture: HAMP:288:0.0000000893:360:73:69#His_kinase:375:7.38e-28:453:80:80#HATPase_c:464:0.0000000000221:574:113:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000157195::NZ_GG670372.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span550959-554182Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFDG_02277RefSeq proteinWP_002395515.1
Context group IDGCF_000157195::NZ_GG670372.1::G00017
Context members
EFDG_RS08470EFDG_RS08475
Partner locus tags
EFDG_RS08470EFDG_RS08475
Partner old locus tags
EFDG_02277EFDG_02278
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002395515.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFDG_RS08470Primary locus identifier stored in the genes table.
Old locus tagEFDG_02277Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG670372.1Sequence record reported by the local genomic context database.
Genomic interval550 959-552 689 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span550 959-554 182 ntGCF_000157195::NZ_GG670372.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157195::NZ_GG670372.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG670372.1All displayed genes belong to this local TCS context.
Neighborhood span550 959-554 182 nt3 224 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
550 959 nt554 182 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFDG_RS08470GCF_000157195#EFDG_RS08470
HKClassicCurrent focus

550 959-552 689 nt · Forward (+)

Old locus EFDG_02277RefSeq WP_002395515.1
EFDG_RS08475GCF_000157195#EFDG_RS08475
RRunclassified

552 701-554 182 nt · Forward (+)

Old locus EFDG_02278RefSeq WP_002359882.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1182886Run 6 · HK · 114 sequences
Representative sequenceGCF_000147455#HMPREF9519_RS09690Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1182886

Simplified PFAM architecture for HKOC_1182886

PFAM domain coverage: 180 / 576 aa (31.3%)

1 aa576 aa
His_kinase: 375-453 aaHis_kinaseHATPase_c: 474-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
  • Domain count: 2
  • Matched identifier: HKOC_1182886
  • Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147455#HMPREF9519_RS09690

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 642 · GCF_000157195
AssemblyASM15719v1 · Scaffoldhaploid
Genome composition3 036 165 bp · 37,5% GCEnterococcus faecalis ATCC 4200
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key