Gene detail

QAE_RS0212650

Histidine kinase, Classic

Clostridioides difficile QCD-23m63 · GCF_000155065

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000155065#QAE_RS0212650Stable P2CS identifier used across views.
GenomeGCF_000155065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0598846Run 6 · 311 sequences · id 100% · cov 80% · representative
External referencesWP_003416282.1 · D5Q276 · MIST4 QAE_RS0212650RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
HisKA: 558-624 aa (67 aa)1HATPase_c: 671-775 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.83e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000141:775:110:109
  • Raw architecture: HisKA:558:1.83e-18:624:67:64#HATPase_c:671:0.000000000141:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000155065::NZ_CM000660.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2657496-2660520Genomic interval covered by the local TCS group.
Context group IDGCF_000155065::NZ_CM000660.1::G00036
Context members
QAE_RS0212650QAE_RS0212655
Partner locus tags
QAE_RS0212650QAE_RS0212655
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003416282.1Primary protein accession used for annex mappings.
UniProt accessionD5Q276Primary UniProt accession resolved in the annex database.
UniProt IDD5Q276_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAE_RS0212650Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000660.1Sequence record reported by the local genomic context database.
Genomic interval2 657 496-2 659 832 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 657 496-2 660 520 ntGCF_000155065::NZ_CM000660.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000155065::NZ_CM000660.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000660.1All displayed genes belong to this local TCS context.
Neighborhood span2 657 496-2 660 520 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 657 496 nt2 660 520 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAE_RS0212655GCF_000155065#QAE_RS0212655
RROmpR

2 659 798-2 660 520 nt · Reverse (-)

RefSeq WP_009905981.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0598846Run 6 · HK · 311 sequences
Representative sequenceGCF_000155065#QAE_RS0212650The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0598846

Simplified PFAM architecture for HKOC_0598846

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0598846
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0212650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 499 174 · GCF_000155065
AssemblyASM15506v1 · Chromosomehaploid
Genome composition3 940 285 bp · 28,5% GCClostridioides difficile QCD-23m63
Signal transduction countsGenes 97 · HK 46 · RR 50CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key