1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw token
HAMP:166:0.0000201:232:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QAE_RS0208280
Histidine kinase, Classic
Clostridioides difficile QCD-23m63 · GCF_000155065
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000155065#QAE_RS0208280Stable P2CS identifier used across views.
GenomeGCF_000155065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 467 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation3 items
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw token
HisKA:245:0.0000000000000228:312:68:643 HATPase_c#3
359-464 aa · 106 aa · 22.7% of protein
Raw token
HATPase_c:359:8.85e-25:464:107:109- Raw architecture: HAMP:166:0.0000201:232:69:69#HisKA:245:0.0000000000000228:312:68:64#HATPase_c:359:8.85e-25:464:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000155065::NZ_CM000660.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1725634-1727766Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000155065::NZ_CM000660.1::G00022Context members
QAE_RS0208275QAE_RS0208280
Partner locus tags
QAE_RS0208275QAE_RS0208280
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003420354.1Primary protein accession used for annex mappings.
UniProt accessionD5Q6Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q6Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQAE_RS0208280Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000660.1Sequence record reported by the local genomic context database.
Genomic interval1 726 363-1 727 766 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 725 634-1 727 766 ntGCF_000155065::NZ_CM000660.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000155065::NZ_CM000660.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000660.1All displayed genes belong to this local TCS context.
Neighborhood span1 725 634-1 727 766 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 725 634 nt1 727 766 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QAE_RS0208275GCF_000155065#QAE_RS0208275
RROmpR
1 725 634-1 726 359 nt · Forward (+)
QAE_RS0208280GCF_000155065#QAE_RS0208280
HKClassicCurrent focus
1 726 363-1 727 766 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0208280The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1747751
Simplified PFAM architecture for HKOC_1747751
PFAM domain coverage: 172 / 467 aa (36.8%)
1 aa467 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-309] | HATPase_c[359-465]
- Domain count: 2
- Matched identifier: HKOC_1747751
- Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0208280
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 499 174 · GCF_000155065
AssemblyASM15506v1 · Chromosomehaploid
Genome composition3 940 285 bp · 28,5% GCClostridioides difficile QCD-23m63
Signal transduction countsGenes 97 · HK 46 · RR 50CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key