Gene detail

EAA_RS02000000218785

Histidine kinase, CheA

Clostridioides difficile CIP 107932 · GCF_000155045

ClassHKTypeCheALength655 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000155045#EAA_RS02000000218785Stable P2CS identifier used across views.
GenomeGCF_000155045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0883347Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_009904021.1 · MIST4 EAA_RS02000000218785RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length655 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage389 / 655 aa (59.4%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa655 aa
Hpt: 10-113 aa (104 aa)1H-kinase_dim: 319-380 aa (62 aa)2HATPase_c: 427-566 aa (140 aa)3CheW: 571-653 aa (83 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
10-113 aa · 104 aa · 15.9% of protein
Raw tokenHpt:10:0.0000000000000209:113:104:84
2 H-kinase_dim#2
319-380 aa · 62 aa · 9.5% of protein
Raw tokenH-kinase_dim:319:0.00000000000000492:380:67:67
3 HATPase_c#3
427-566 aa · 140 aa · 21.4% of protein
Raw tokenHATPase_c:427:8.34e-18:566:140:109
4 CheW#4
571-653 aa · 83 aa · 12.7% of protein
Raw tokenCheW:571:0.0000000322:653:84:138
  • Raw architecture: Hpt:10:0.0000000000000209:113:104:84#H-kinase_dim:319:0.00000000000000492:380:67:67#HATPase_c:427:8.34e-18:566:140:109#CheW:571:0.0000000322:653:84:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000155045::NZ_CM000659.1::G00011
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span518935-520902Genomic interval covered by the local TCS group.
Context group IDGCF_000155045::NZ_CM000659.1::G00011
Context members
EAA_RS02000000218785
Partner locus tags
EAA_RS02000000218785
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009904021.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEAA_RS02000000218785Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000659.1Sequence record reported by the local genomic context database.
Genomic interval518 935-520 902 nt1 968 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span518 935-520 902 ntGCF_000155045::NZ_CM000659.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000155045::NZ_CM000659.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000659.1All displayed genes belong to this local TCS context.
Neighborhood span518 935-520 902 nt1 968 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
518 935 nt520 902 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0883347Run 6 · HK · 1 sequences
Representative sequenceGCF_000155045#EAA_RS02000000218785The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0883347

Simplified PFAM architecture for HKOC_0883347

PFAM domain coverage: 461 / 655 aa (70.4%)

1 aa655 aa
Hpt: 10-111 aaHptP2: 171-247 aaP2H-kinase_dim: 319-380 aaH-kinase_dimHATPase_c: 429-566 aaHATPase_cCheW: 572-653 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[10-111] | P2[171-247] | H-kinase_dim[319-380] | HATPase_c[429-566] | CheW[572-653]
  • Domain count: 5
  • Matched identifier: HKOC_0883347
  • Positioned domains: Hpt 10-111 ; P2 171-247 ; H-kinase_dim 319-380 ; HATPase_c 429-566 ; CheW 572-653
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155045#EAA_RS02000000218785

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 499 176 · GCF_000155045
Assemblycdeaa · Chromosomehaploid
Genome composition4 036 680 bp · 28,5% GCClostridioides difficile CIP 107932
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key