Gene detail

AEC_RS0215225

Histidine kinase, Classic

Clostridioides difficile QCD-37x79 · GCF_000154685

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154685#AEC_RS0215225Stable P2CS identifier used across views.
GenomeGCF_000154685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2071540Run 6 · 2254 sequences · id 100% · cov 80%
External referencesWP_004454160.1 · A0A0H3N4Z3 · MIST4 AEC_RS0215225RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 440 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 156-222 aa (67 aa)1HisKA: 233-291 aa (59 aa)2HATPase_c: 348-439 aa (92 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
156-222 aa · 67 aa · 15.2% of protein
Raw tokenHAMP:156:0.000000000583:222:70:69
2 HisKA#2
233-291 aa · 59 aa · 13.4% of protein
Raw tokenHisKA:233:0.00000000021:291:59:64
3 HATPase_c#3
348-439 aa · 92 aa · 20.9% of protein
Raw tokenHATPase_c:348:0.0000000149:439:108:109
  • Raw architecture: HAMP:156:0.000000000583:222:70:69#HisKA:233:0.00000000021:291:59:64#HATPase_c:348:0.0000000149:439:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154685::NZ_CM000658.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2930512-2932531Genomic interval covered by the local TCS group.
Context group IDGCF_000154685::NZ_CM000658.1::G00045
Context members
AEC_RS0215225AEC_RS0215230
Partner locus tags
AEC_RS0215225AEC_RS0215230
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454160.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4Z3Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4Z3_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAEC_RS0215225Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000658.1Sequence record reported by the local genomic context database.
Genomic interval2 930 512-2 931 834 nt1 323 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 930 512-2 932 531 ntGCF_000154685::NZ_CM000658.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154685::NZ_CM000658.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000658.1All displayed genes belong to this local TCS context.
Neighborhood span2 930 512-2 932 531 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 930 512 nt2 932 531 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AEC_RS0215230GCF_000154685#AEC_RS0215230
RROmpR

2 931 827-2 932 531 nt · Reverse (-)

RefSeq WP_003426384.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2071540Run 6 · HK · 2254 sequences
Representative sequenceGCF_000003215#QAC_RS0213755Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2071540

Simplified PFAM architecture for HKOC_2071540

PFAM domain coverage: 169 / 440 aa (38.4%)

1 aa440 aa
HAMP: 177-221 aaHAMPHisKA: 235-291 aaHisKAHATPase_c_5: 370-436 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[177-221] | HisKA[235-291] | HATPase_c_5[370-436]
  • Domain count: 3
  • Matched identifier: HKOC_2071540
  • Positioned domains: HAMP 177-221 ; HisKA 235-291 ; HATPase_c_5 370-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0213755

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 2 254 total members. Page 1 / 46.

GCF_000003215#QAC_RS0213755 (representative)
QAC_RS0213755 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000009205#CD630_RS14560
CD630_RS14560 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000027105#CDR20291_RS14120
CDR20291_RS14120 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000085225#CD196_RS13835
CD196_RS13835 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000154625#QAB_RS0216065
QAB_RS0216065 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000154645#UAA_RS0215660
UAA_RS0215660 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000154665#QAD_RS0213895
QAD_RS0213895 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000154685#AEC_RS0215225
AEC_RS0215225 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000155025#UAB_RS0214935
UAB_RS0214935 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000155045#EAA_RS0213650
EAA_RS0213650 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000210455#CD7855_RS13625
CD7855_RS13625 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000211235#CDBI1_RS13715
CDBI1_RS13715 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000235905#HMPREF9945_RS11180
HMPREF9945_RS11180 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000242355#MUI_RS0107830
MUI_RS0107830 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000376285#B131_RS0103655
B131_RS0103655 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000438845#M018_RS0105060
M018_RS0105060 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448725#QAW_RS14475
QAW_RS14475 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448745#QC1_RS14415
QC1_RS14415 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448765#QC5_RS13815
QC5_RS13815 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448805#QKI_RS14800
QKI_RS14800 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448825#QAO_RS13465
QAO_RS13465 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448845#QAQ_RS13515
QAQ_RS13515 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448865#QAS_RS14235
QAS_RS14235 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448885#QAU_RS14075
QAU_RS14075 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448905#QAY_RS13440
QAY_RS13440 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448925#QC7_RS14270
QC7_RS14270 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448965#QCA_RS14330
QCA_RS14330 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000448985#QCC_RS13410
QCC_RS13410 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449005#QCE_RS13945
QCE_RS13945 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449025#QCG_RS14460
QCG_RS14460 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449045#QCI_RS13765
QCI_RS13765 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449065#QCK_RS15685
QCK_RS15685 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449085#QCM_RS13545
QCM_RS13545 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449105#QCO_RS14190
QCO_RS14190 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449125#QCQ_RS14270
QCQ_RS14270 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449165#QCU_RS13455
QCU_RS13455 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449205#QMQ_RS14005
QMQ_RS14005 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449225#QCY_RS13960
QCY_RS13960 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449245#QEA_RS14280
QEA_RS14280 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449265#QMK_RS13985
QMK_RS13985 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449305#QEK_RS14665
QEK_RS14665 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449325#QEM_RS12755
QEM_RS12755 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449345#QEO_RS14035
QEO_RS14035 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449365#QEQ_RS14110
QEQ_RS14110 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449385#QES_RS15295
QES_RS15295 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449405#QEU_RS13565
QEU_RS13565 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449445#QEY_RS13710
QEY_RS13710 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449465#QG1_RS15190
QG1_RS15190 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449485#QG3_RS13265
QG3_RS13265 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3
GCF_000449505#QG5_RS14780
QG5_RS14780 · HK · Classic
RefSeq: WP_004454160.1
UniProt: A0A0H3N4Z3

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 479 834 · GCF_000154685
Assemblycdqaf · Chromosomehaploid
Genome composition4 332 988 bp · 28,5% GCClostridioides difficile QCD-37x79
Signal transduction countsGenes 107 · HK 50 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key