Gene detail

QAD_RS0209385

Histidine kinase, Classic

Clostridioides difficile QCD-97b34 · GCF_000154665

ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154665#QAD_RS0209385Stable P2CS identifier used across views.
GenomeGCF_000154665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1645510Run 6 · 2636 sequences · id 100% · cov 80%
External referencesWP_003430278.1 · A0A0H3N3K5 · MIST4 QAD_RS0209385RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 477 aa (50.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa477 aa
HAMP: 177-246 aa (70 aa)1HisKA: 253-317 aa (65 aa)2HATPase_c: 365-470 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
177-246 aa · 70 aa · 14.7% of protein
Raw tokenHAMP:177:0.00000000000000602:246:70:69
2 HisKA#2
253-317 aa · 65 aa · 13.6% of protein
Raw tokenHisKA:253:1.02e-16:317:65:64
3 HATPase_c#3
365-470 aa · 106 aa · 22.2% of protein
Raw tokenHATPase_c:365:6.76e-28:470:107:109
  • Raw architecture: HAMP:177:0.00000000000000602:246:70:69#HisKA:253:1.02e-16:317:65:64#HATPase_c:365:6.76e-28:470:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154665::NZ_CM000657.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1897747-1899881Genomic interval covered by the local TCS group.
Context group IDGCF_000154665::NZ_CM000657.1::G00030
Context members
QAD_RS0209380QAD_RS0209385
Partner locus tags
QAD_RS0209380QAD_RS0209385
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003430278.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N3K5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N3K5_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAD_RS0209385Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000657.1Sequence record reported by the local genomic context database.
Genomic interval1 898 448-1 899 881 nt1 434 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 897 747-1 899 881 ntGCF_000154665::NZ_CM000657.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154665::NZ_CM000657.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000657.1All displayed genes belong to this local TCS context.
Neighborhood span1 897 747-1 899 881 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 897 747 nt1 899 881 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAD_RS0209380GCF_000154665#QAD_RS0209380
RROmpR

1 897 747-1 898 445 nt · Forward (+)

RefSeq WP_009889742.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1645510Run 6 · HK · 2636 sequences
Representative sequenceGCF_000003215#QAC_RS0209215Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1645510

Simplified PFAM architecture for HKOC_1645510

PFAM domain coverage: 220 / 477 aa (46.1%)

1 aa477 aa
HAMP: 197-246 aaHAMPHisKA: 253-316 aaHisKAHATPase_c: 365-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[197-246] | HisKA[253-316] | HATPase_c[365-470]
  • Domain count: 3
  • Matched identifier: HKOC_1645510
  • Positioned domains: HAMP 197-246 ; HisKA 253-316 ; HATPase_c 365-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209215

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 479 833 · GCF_000154665
AssemblyASM15466v1 · Chromosomehaploid
Genome composition4 063 610 bp · 28,5% GCClostridioides difficile QCD-97b34
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key