Gene detail

QAB_RS0211795

Histidine kinase, Classic

Clostridioides difficile QCD-63q42 · GCF_000154625

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154625#QAB_RS0211795Stable P2CS identifier used across views.
GenomeGCF_000154625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0878348Run 6 · 1724 sequences · id 100% · cov 80%
External referencesWP_003435429.1 · Q187M1 · MIST4 QAB_RS0211795RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
H_kinase_N: 12-142 aa (131 aa)1HisKA_2: 276-350 aa (75 aa)2HATPase_c: 370-467 aa (98 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.53e-36:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.46e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.0000000689:467:114:109
  • Raw architecture: H_kinase_N:12:1.53e-36:142:132:139#HisKA_2:276:2.46e-16:350:76:76#HATPase_c:370:0.0000000689:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154625::NZ_CM000637.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2029888-2031865Genomic interval covered by the local TCS group.
Context group IDGCF_000154625::NZ_CM000637.1::G00032
Context members
QAB_RS0211790QAB_RS0211795
Partner locus tags
QAB_RS0211790QAB_RS0211795
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003435429.1Primary protein accession used for annex mappings.
UniProt accessionQ187M1Primary UniProt accession resolved in the annex database.
UniProt IDQ187M1_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAB_RS0211795Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000637.1Sequence record reported by the local genomic context database.
Genomic interval2 030 456-2 031 865 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 029 888-2 031 865 ntGCF_000154625::NZ_CM000637.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154625::NZ_CM000637.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000637.1All displayed genes belong to this local TCS context.
Neighborhood span2 029 888-2 031 865 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 029 888 nt2 031 865 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAB_RS0211790GCF_000154625#QAB_RS0211790
RRAmiR_NasR

2 029 888-2 030 463 nt · Forward (+)

RefSeq WP_003423977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0878348Run 6 · HK · 1724 sequences
Representative sequenceGCF_041537345#ACD536_RS00630Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0878348

Simplified PFAM architecture for HKOC_0878348

PFAM domain coverage: 466 / 658 aa (70.8%)

1 aa658 aa
Response_reg: 5-115 aaResponse_regANTAR: 134-186 aaANTARGAF_PdtaS: 195-330 aaGAF_PdtaSHisKA_2: 465-536 aaHisKA_2HATPase_c: 562-655 aaHATPase_c
Response_regANTARGAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: Response_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: Response_reg[5-115] | ANTAR[134-186] | GAF_PdtaS[195-330] | HisKA_2[465-536] | HATPase_c[562-655]
  • Domain count: 5
  • Matched identifier: HKOC_0878348
  • Positioned domains: Response_reg 5-115 ; ANTAR 134-186 ; GAF_PdtaS 195-330 ; HisKA_2 465-536 ; HATPase_c 562-655
Cluster members and taxonomy
Visualization

Representative gene: GCF_041537345#ACD536_RS00630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 479 831 · GCF_000154625
AssemblyASM15462v1 · Chromosomehaploid
Genome composition4 443 737 bp · 28,5% GCClostridioides difficile QCD-63q42
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key