1 GAF#1
244-363 aa · 120 aa · 20.7% of protein
Raw token
GAF:244:0.00000133:363:128:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9496_RS14820
Histidine kinase, Classic
Enterococcus faecalis TX4000 · GCF_000148445
ClassHKTypeClassicLength579 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148445#HMPREF9496_RS14820Stable P2CS identifier used across views.
GenomeGCF_000148445Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length579 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage303 / 579 aa (52.3%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa579 aa
Domain-by-domain annotation3 items
2 His_kinase#2
378-456 aa · 79 aa · 13.6% of protein
Raw token
His_kinase:378:2.45e-30:456:80:803 HATPase_c#3
476-579 aa · 104 aa · 18.0% of protein
Raw token
HATPase_c:476:0.00000000000146:579:108:109- Raw architecture: GAF:244:0.00000133:363:128:133#His_kinase:378:2.45e-30:456:80:80#HATPase_c:476:0.00000000000146:579:108:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000148445::NZ_GL476295.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3480-5958Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9496_02389RefSeq proteinWP_002388628.1
Context group ID
GCF_000148445::NZ_GL476295.1::G00013Context members
HMPREF9496_RS14815HMPREF9496_RS14820
Partner locus tags
HMPREF9496_RS14815HMPREF9496_RS14820
Partner old locus tags
HMPREF9496_02388HMPREF9496_02389
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002388628.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9496_RS14820Primary locus identifier stored in the genes table.
Old locus tagHMPREF9496_02389Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL476295.1Sequence record reported by the local genomic context database.
Genomic interval4 219-5 958 nt1 740 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 480-5 958 ntGCF_000148445::NZ_GL476295.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000148445::NZ_GL476295.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL476295.1All displayed genes belong to this local TCS context.
Neighborhood span3 480-5 958 nt2 479 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 480 nt5 958 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9496_RS14815GCF_000148445#HMPREF9496_RS14815
RRLytTR
3 480-4 208 nt · Reverse (-)
HMPREF9496_RS14820GCF_000148445#HMPREF9496_RS14820
HKClassicCurrent focus
4 219-5 958 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147455#HMPREF9519_RS13480Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1114761
Simplified PFAM architecture for HKOC_1114761
PFAM domain coverage: 364 / 589 aa (61.8%)
1 aa589 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[26-206] | His_kinase[378-456] | HATPase_c[476-579]
- Domain count: 3
- Matched identifier: HKOC_1114761
- Positioned domains: 5TM-5TMR_LYT 26-206 ; His_kinase 378-456 ; HATPase_c 476-579
Cluster members and taxonomy
Representative gene: GCF_000147455#HMPREF9519_RS13480
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 493 · GCF_000148445
AssemblyASM14844v1 · Scaffoldhaploid
Genome composition2 840 305 bp · 37,5% GCEnterococcus faecalis TX4000
Signal transduction countsGenes 30 · HK 14 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key