Gene detail

HMPREF9524_RS10155

Histidine kinase, Classic

Enterococcus faecium TX0133a01 · GCF_000148325

ClassHKTypeClassicLength346 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148325#HMPREF9524_RS10155Stable P2CS identifier used across views.
GenomeGCF_000148325Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2815358Run 6 · 248 sequences · id 100% · cov 80%
External referencesWP_002301716.1 · A0AB73NMP5 · MIST4 HMPREF9524_RS10155RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length346 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 346 aa (70.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa346 aa
HAMP: 54-123 aa (70 aa)1HisKA: 129-194 aa (66 aa)2HATPase_c: 238-344 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
54-123 aa · 70 aa · 20.2% of protein
Raw tokenHAMP:54:0.0000000125:123:70:69
2 HisKA#2
129-194 aa · 66 aa · 19.1% of protein
Raw tokenHisKA:129:0.0000000000000119:194:66:64
3 HATPase_c#3
238-344 aa · 107 aa · 30.9% of protein
Raw tokenHATPase_c:238:7.11e-32:344:107:109
  • Raw architecture: HAMP:54:0.0000000125:123:70:69#HisKA:129:0.0000000000000119:194:66:64#HATPase_c:238:7.11e-32:344:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000148325::NZ_GL476143.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27410-29121Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9524_02183RefSeq proteinWP_002301716.1
Context group IDGCF_000148325::NZ_GL476143.1::G00016
Context members
HMPREF9524_RS10155HMPREF9524_RS10160
Partner locus tags
HMPREF9524_RS10155HMPREF9524_RS10160
Partner old locus tags
HMPREF9524_02183HMPREF9524_02184
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002301716.1Primary protein accession used for annex mappings.
UniProt accessionA0AB73NMP5Primary UniProt accession resolved in the annex database.
UniProt IDA0AB73NMP5_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9524_RS10155Primary locus identifier stored in the genes table.
Old locus tagHMPREF9524_02183Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL476143.1Sequence record reported by the local genomic context database.
Genomic interval27 410-28 450 nt1 041 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 410-29 121 ntGCF_000148325::NZ_GL476143.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000148325::NZ_GL476143.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL476143.1All displayed genes belong to this local TCS context.
Neighborhood span27 410-29 121 nt1 712 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 410 nt29 121 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9524_RS10160GCF_000148325#HMPREF9524_RS10160
RROmpR

28 453-29 121 nt · Reverse (-)

Old locus HMPREF9524_02184RefSeq WP_002297412.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2815358Run 6 · HK · 248 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS10515Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2815358

Simplified PFAM architecture for HKOC_2815358

PFAM domain coverage: 225 / 346 aa (65.0%)

1 aa346 aa
HAMP: 71-123 aaHAMPHisKA: 129-193 aaHisKAHATPase_c: 238-344 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[71-123] | HisKA[129-193] | HATPase_c[238-344]
  • Domain count: 3
  • Matched identifier: HKOC_2815358
  • Positioned domains: HAMP 71-123 ; HisKA 129-193 ; HATPase_c 238-344
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS10515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 522 · GCF_000148325
AssemblyASM14832v1 · Scaffoldhaploid
Genome composition3 073 581 bp · 37,5% GCEnterococcus faecium TX0133a01
Signal transduction countsGenes 39 · HK 18 · RR 21CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key