Gene detail

HMPREF9523_RS00795

Histidine kinase, Classic

Enterococcus faecium TX0133A · GCF_000148285

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148285#HMPREF9523_RS00795Stable P2CS identifier used across views.
GenomeGCF_000148285Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1057257Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_002321535.1 · MIST4 HMPREF9523_RS00795RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage355 / 599 aa (59.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
HAMP: 182-248 aa (67 aa)1PAS: 249-356 aa (108 aa)2HisKA: 365-432 aa (68 aa)3HATPase_c: 481-592 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
182-248 aa · 67 aa · 11.2% of protein
Raw tokenHAMP:182:4.48e-17:248:67:69
2 PAS#2
249-356 aa · 108 aa · 18.0% of protein
Raw tokenPAS:249:0.00000000193:356:113:113
3 HisKA#3
365-432 aa · 68 aa · 11.4% of protein
Raw tokenHisKA:365:7.02e-19:432:68:64
4 HATPase_c#4
481-592 aa · 112 aa · 18.7% of protein
Raw tokenHATPase_c:481:7.37e-32:592:112:109
  • Raw architecture: HAMP:182:4.48e-17:248:67:69#PAS:249:0.00000000193:356:113:113#HisKA:365:7.02e-19:432:68:64#HATPase_c:481:7.37e-32:592:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000148285::NZ_GL456557.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8499-11007Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9523_00183RefSeq proteinWP_002321535.1
Context group IDGCF_000148285::NZ_GL456557.1::G00002
Context members
HMPREF9523_RS00795HMPREF9523_RS00800
Partner locus tags
HMPREF9523_RS00795HMPREF9523_RS00800
Partner old locus tags
HMPREF9523_00183HMPREF9523_00184
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002321535.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9523_RS00795Primary locus identifier stored in the genes table.
Old locus tagHMPREF9523_00183Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL456557.1Sequence record reported by the local genomic context database.
Genomic interval8 499-10 298 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 499-11 007 ntGCF_000148285::NZ_GL456557.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000148285::NZ_GL456557.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL456557.1All displayed genes belong to this local TCS context.
Neighborhood span8 499-11 007 nt2 509 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 499 nt11 007 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9523_RS00800GCF_000148285#HMPREF9523_RS00800
RROmpR

10 303-11 007 nt · Reverse (-)

Old locus HMPREF9523_00184RefSeq WP_002288850.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1057257Run 6 · HK · 2 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS11935Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1057257

Simplified PFAM architecture for HKOC_1057257

PFAM domain coverage: 378 / 599 aa (63.1%)

1 aa599 aa
Cache_WalK: 79-166 aaCache_WalKHAMP: 199-248 aaHAMPPAS: 250-311 aaPASHisKA: 366-432 aaHisKAHATPase_c: 481-591 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-166] | HAMP[199-248] | PAS[250-311] | HisKA[366-432] | HATPase_c[481-591]
  • Domain count: 5
  • Matched identifier: HKOC_1057257
  • Positioned domains: Cache_WalK 79-166 ; HAMP 199-248 ; PAS 250-311 ; HisKA 366-432 ; HATPase_c 481-591
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS11935

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 521 · GCF_000148285
AssemblyASM14828v1 · Scaffoldhaploid
Genome composition2 930 324 bp · 37,5% GCEnterococcus faecium TX0133A
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key