1 HisKA#1
146-209 aa · 64 aa · 17.3% of protein
Raw token
HisKA:146:0.000000000034:209:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9521_RS12405
Histidine kinase, Classic
Enterococcus faecalis TX2134 · GCF_000148065
ClassHKTypeClassicLength370 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148065#HMPREF9521_RS12405Stable P2CS identifier used across views.
GenomeGCF_000148065Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length370 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 370 aa (46.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa370 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
259-367 aa · 109 aa · 29.5% of protein
Raw token
HATPase_c:259:1.17e-24:367:110:109- Raw architecture: HisKA:146:0.000000000034:209:64:64#HATPase_c:259:1.17e-24:367:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000148065::NZ_GL455611.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18303-20112Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9521_01786RefSeq proteinWP_002365141.1
Context group ID
GCF_000148065::NZ_GL455611.1::G00010Context members
HMPREF9521_RS12405HMPREF9521_RS12410
Partner locus tags
HMPREF9521_RS12405HMPREF9521_RS12410
Partner old locus tags
HMPREF9521_01786HMPREF9521_01787
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002365141.1Primary protein accession used for annex mappings.
UniProt accessionA0A125W9B4Primary UniProt accession resolved in the annex database.
UniProt IDA0A125W9B4_ENTFLDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9521_RS12405Primary locus identifier stored in the genes table.
Old locus tagHMPREF9521_01786Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL455611.1Sequence record reported by the local genomic context database.
Genomic interval18 303-19 415 nt1 113 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 303-20 112 ntGCF_000148065::NZ_GL455611.1::G00010
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000148065::NZ_GL455611.1::G00010Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL455611.1All displayed genes belong to this local TCS context.
Neighborhood span18 303-20 112 nt1 810 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 303 nt20 112 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9521_RS12405GCF_000148065#HMPREF9521_RS12405
HKClassicCurrent focus
18 303-19 415 nt · Reverse (-)
HMPREF9521_RS12410GCF_000148065#HMPREF9521_RS12410
RROmpR
19 408-20 112 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147215#HMPREF9504_RS04285Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2682651
Simplified PFAM architecture for HKOC_2682651
PFAM domain coverage: 173 / 370 aa (46.8%)
1 aa370 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-210] | HATPase_c[259-367]
- Domain count: 2
- Matched identifier: HKOC_2682651
- Positioned domains: HisKA 147-210 ; HATPase_c 259-367
Cluster members and taxonomy
Representative gene: GCF_000147215#HMPREF9504_RS04285
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 518 · GCF_000148065
AssemblyASM14806v1 · Scaffoldhaploid
Genome composition3 121 432 bp · 37,0% GCEnterococcus faecalis TX2134
Signal transduction countsGenes 31 · HK 15 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key