1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.0000000000000134:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDR20291_RS12035
Histidine kinase, Classic
Clostridioides difficile R20291 · GCF_000027105
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000027105#CDR20291_RS12035Stable P2CS identifier used across views.
GenomeGCF_000027105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa530 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.0000000388:513:90:109- Raw architecture: HisKA:309:0.0000000000000134:375:67:64#HATPase_c:428:0.0000000388:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000027105::NC_013316.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2588735-2591012Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDR20291_2206RefSeq proteinWP_009893576.1
Context group ID
GCF_000027105::NC_013316.1::G00041Context members
CDR20291_RS12030CDR20291_RS12035
Partner locus tags
CDR20291_RS12030CDR20291_RS12035
Partner old locus tags
CDR20291_2205CDR20291_2206
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009893576.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R630Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R630_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDR20291_RS12035Primary locus identifier stored in the genes table.
Old locus tagCDR20291_2206Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_013316.1Sequence record reported by the local genomic context database.
Genomic interval2 589 420-2 591 012 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 588 735-2 591 012 ntGCF_000027105::NC_013316.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000027105::NC_013316.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_013316.1All displayed genes belong to this local TCS context.
Neighborhood span2 588 735-2 591 012 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 588 735 nt2 591 012 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDR20291_RS12030GCF_000027105#CDR20291_RS12030
RROmpR
2 588 735-2 589 451 nt · Forward (+)
CDR20291_RS12035GCF_000027105#CDR20291_RS12035
HKClassicCurrent focus
2 589 420-2 591 012 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0211650Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1355490
Simplified PFAM architecture for HKOC_1355490
PFAM domain coverage: 191 / 530 aa (36.0%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
- Domain count: 3
- Matched identifier: HKOC_1355490
- Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0211650
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 645 463 · GCF_000027105
AssemblyASM2710v1 · Chromosomehaploid
Genome composition4 191 339 bp · 29,0% GCClostridioides difficile R20291
Signal transduction countsGenes 108 · HK 51 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key