Gene detail

ECDH1_RS08935

Histidine kinase, Classic

Escherichia coli DH1 · GCF_000023365

ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000023365#ECDH1_RS08935Stable P2CS identifier used across views.
GenomeGCF_000023365Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1936926Run 6 · 839 sequences · id 100% · cov 80%
External referencesWP_000826792.1 · MIST4 ECDH1_RS08935RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 452 aa (53.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
HAMP: 161-229 aa (69 aa)1HisKA: 235-299 aa (65 aa)2HATPase_c: 344-452 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-229 aa · 69 aa · 15.3% of protein
Raw tokenHAMP:161:0.000000000745:229:69:69
2 HisKA#2
235-299 aa · 65 aa · 14.4% of protein
Raw tokenHisKA:235:0.0000000000751:299:65:64
3 HATPase_c#3
344-452 aa · 109 aa · 24.1% of protein
Raw tokenHATPase_c:344:3.89e-17:452:113:109
  • Raw architecture: HAMP:161:0.000000000745:229:69:69#HisKA:235:0.0000000000751:299:65:64#HATPase_c:344:3.89e-17:452:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000023365::NC_017625.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1839232-1841261Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEcDH1_1683RefSeq proteinWP_000826792.1
Context group IDGCF_000023365::NC_017625.1::G00017
Context members
ECDH1_RS08930ECDH1_RS08935
Partner locus tags
ECDH1_RS08930ECDH1_RS08935
Partner old locus tags
EcDH1_1682EcDH1_1683
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_000826792.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECDH1_RS08935Primary locus identifier stored in the genes table.
Old locus tagEcDH1_1683Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017625.1Sequence record reported by the local genomic context database.
Genomic interval1 839 903-1 841 261 nt1 359 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 839 232-1 841 261 ntGCF_000023365::NC_017625.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000023365::NC_017625.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017625.1All displayed genes belong to this local TCS context.
Neighborhood span1 839 232-1 841 261 nt2 030 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 839 232 nt1 841 261 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECDH1_RS08930GCF_000023365#ECDH1_RS08930
RROmpR

1 839 232-1 839 903 nt · Forward (+)

Old locus EcDH1_1682RefSeq WP_001395354.1
ECDH1_RS08935GCF_000023365#ECDH1_RS08935
HKClassicCurrent focus

1 839 903-1 841 261 nt · Forward (+)

Old locus EcDH1_1683RefSeq WP_000826792.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1936926Run 6 · HK · 839 sequences
Representative sequenceGCF_000005845#b1968Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1936926

Simplified PFAM architecture for HKOC_1936926

PFAM domain coverage: 172 / 452 aa (38.1%)

1 aa452 aa
HisKA: 236-300 aaHisKAHATPase_c: 345-451 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[236-300] | HATPase_c[345-451]
  • Domain count: 2
  • Matched identifier: HKOC_1936926
  • Positioned domains: HisKA 236-300 ; HATPase_c 345-451
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b1968

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 056 · GCF_000023365
AssemblyASM2336v1 · Complete Genomehaploid
Genome composition4 630 707 bp · 51,0% GCEscherichia coli DH1
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key