1 Hpt#1
7-93 aa · 87 aa · 13.3% of protein
Raw token
Hpt:7:0.0000000000000011:93:87:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BWG_RS09355
Histidine kinase, CheA
Escherichia coli BW2952 · GCF_000022345
ClassHKTypeCheALength654 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000022345#BWG_RS09355Stable P2CS identifier used across views.
GenomeGCF_000022345Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length654 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage415 / 654 aa (63.5%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa654 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
263-324 aa · 62 aa · 9.5% of protein
Raw token
H-kinase_dim:263:1.45e-18:324:66:673 HATPase_c#3
371-508 aa · 138 aa · 21.1% of protein
Raw token
HATPase_c:371:5.56e-17:508:138:1094 CheW#4
513-640 aa · 128 aa · 19.6% of protein
Raw token
CheW:513:5.99e-30:640:134:138- Raw architecture: Hpt:7:0.0000000000000011:93:87:84#H-kinase_dim:263:1.45e-18:324:66:67#HATPase_c:371:5.56e-17:508:138:109#CheW:513:5.99e-30:640:134:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000022345::NC_012759.1::G00013
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1863443-1865407Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBWG_1702RefSeq proteinWP_001350517.1
Context group ID
GCF_000022345::NC_012759.1::G00013Context members
BWG_RS09355
Partner locus tags
BWG_RS09355
Partner old locus tags
BWG_1702
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001350517.1Primary protein accession used for annex mappings.
UniProt accessionP07363Primary UniProt accession resolved in the annex database.
UniProt IDCHEA_ECOLIDisplay identifier provided by UniProt.
GO / PubMed18 / 42Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBWG_RS09355Primary locus identifier stored in the genes table.
Old locus tagBWG_1702Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_012759.1Sequence record reported by the local genomic context database.
Genomic interval1 863 443-1 865 407 nt1 965 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 863 443-1 865 407 ntGCF_000022345::NC_012759.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000022345::NC_012759.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_012759.1All displayed genes belong to this local TCS context.
Neighborhood span1 863 443-1 865 407 nt1 965 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 863 443 nt1 865 407 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
BWG_RS09355GCF_000022345#BWG_RS09355
HKCheACurrent focus
1 863 443-1 865 407 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHpt + CheY-binding + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0886030
Simplified PFAM architecture for HKOC_0886030
PFAM domain coverage: 484 / 654 aa (74.0%)
1 aa654 aa
HptCheY-bindingH-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + CheY-binding + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[8-100] | CheY-binding[161-223] | H-kinase_dim[261-324] | HATPase_c[372-508] | CheW[514-640]
- Domain count: 5
- Matched identifier: HKOC_0886030
- Positioned domains: Hpt 8-100 ; CheY-binding 161-223 ; H-kinase_dim 261-324 ; HATPase_c 372-508 ; CheW 514-640
Cluster members and taxonomy
Representative gene: GCF_000005845#b1888
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 595 496 · GCF_000022345
AssemblyASM2234v1 · Complete Genomehaploid
Genome composition4 578 159 bp · 51,0% GCEscherichia coli BW2952
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key