Gene detail

BAMEG_RS23970

Histidine kinase, Classic

Bacillus anthracis str. CDC 684 · GCF_000021445

ClassHKTypeClassicLength587 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000021445#BAMEG_RS23970Stable P2CS identifier used across views.
GenomeGCF_000021445Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1125687Run 6 · 512 sequences · id 100% · cov 80%
External referencesWP_001032128.1 · A0A242W7G4 · MIST4 BAMEG_RS23970RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length587 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 587 aa (80.1%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa587 aa
sCache_like: 35-149 aa (115 aa)1HAMP: 165-234 aa (70 aa)2PAS: 245-351 aa (107 aa)3HisKA: 360-427 aa (68 aa)4HATPase_c: 472-581 aa (110 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-149 aa · 115 aa · 19.6% of protein
Raw tokensCache_like:35:5.3e-25:149:117:114
2 HAMP#2
165-234 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:165:0.00000000000662:234:70:69
3 PAS#3
245-351 aa · 107 aa · 18.2% of protein
Raw tokenPAS:245:0.0000000000000282:351:112:113
4 HisKA#4
360-427 aa · 68 aa · 11.6% of protein
Raw tokenHisKA:360:1.38e-21:427:68:64
5 HATPase_c#5
472-581 aa · 110 aa · 18.7% of protein
Raw tokenHATPase_c:472:5.04e-36:581:110:109
  • Raw architecture: sCache_like:35:5.3e-25:149:117:114#HAMP:165:0.00000000000662:234:70:69#PAS:245:0.0000000000000282:351:112:113#HisKA:360:1.38e-21:427:68:64#HATPase_c:472:5.04e-36:581:110:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000021445::NC_012581.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4396794-4399269Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBAMEG_4863RefSeq proteinWP_001032128.1
Context group IDGCF_000021445::NC_012581.1::G00046
Context members
BAMEG_RS23970BAMEG_RS23975
Partner locus tags
BAMEG_RS23970BAMEG_RS23975
Partner old locus tags
BAMEG_4863BAMEG_4864
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001032128.1Primary protein accession used for annex mappings.
UniProt accessionA0A242W7G4Primary UniProt accession resolved in the annex database.
UniProt IDA0A242W7G4_BACTUDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBAMEG_RS23970Primary locus identifier stored in the genes table.
Old locus tagBAMEG_4863Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_012581.1Sequence record reported by the local genomic context database.
Genomic interval4 396 794-4 398 557 nt1 764 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 396 794-4 399 269 ntGCF_000021445::NC_012581.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000021445::NC_012581.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_012581.1All displayed genes belong to this local TCS context.
Neighborhood span4 396 794-4 399 269 nt2 476 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 396 794 nt4 399 269 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BAMEG_RS23970GCF_000021445#BAMEG_RS23970
HKClassicCurrent focus

4 396 794-4 398 557 nt · Reverse (-)

Old locus BAMEG_4863RefSeq WP_001032128.1
BAMEG_RS23975GCF_000021445#BAMEG_RS23975
RROmpR

4 398 550-4 399 269 nt · Reverse (-)

Old locus BAMEG_4864RefSeq WP_001065226.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1125687Run 6 · HK · 512 sequences
Representative sequenceGCF_000007845#BA_RS22700Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1125687

Simplified PFAM architecture for HKOC_1125687

PFAM domain coverage: 449 / 587 aa (76.5%)

1 aa587 aa
sCache_like: 33-149 aasCache_likeHAMP: 188-234 aaHAMPPAS: 245-351 aaPASHisKA: 360-426 aaHisKAHATPase_c: 472-582 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-149] | HAMP[188-234] | PAS[245-351] | HisKA[360-426] | HATPase_c[472-582]
  • Domain count: 5
  • Matched identifier: HKOC_1125687
  • Positioned domains: sCache_like 33-149 ; HAMP 188-234 ; PAS 245-351 ; HisKA 360-426 ; HATPase_c 472-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007845#BA_RS22700

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 568 206 · GCF_000021445
AssemblyASM2144v1 · Complete Genomehaploid
Genome composition5 506 763 bp · 35,0% GCBacillus anthracis str. CDC 684
Signal transduction countsGenes 96 · HK 46 · RR 49CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key