Gene detail

ECB_RS03440

Histidine kinase, Classic

Escherichia coli B str. REL606 · GCF_000017985

ClassHKTypeClassicLength894 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000017985#ECB_RS03440Stable P2CS identifier used across views.
GenomeGCF_000017985Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0419540Run 6 · 1094 sequences · id 100% · cov 80%
External referencesWP_001301349.1 · A0A1V0MR34 · MIST4 ECB_RS03440RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length894 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage502 / 894 aa (56.2%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa894 aa
KdpD: 21-230 aa (210 aa)1GAF_3: 527-644 aa (118 aa)2HisKA: 664-730 aa (67 aa)3HATPase_c: 774-880 aa (107 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
21-230 aa · 210 aa · 23.5% of protein
Raw tokenKdpD:21:4.38e-143:230:210:210
2 GAF_3#2
527-644 aa · 118 aa · 13.2% of protein
Raw tokenGAF_3:527:0.00000000000403:644:130:129
3 HisKA#3
664-730 aa · 67 aa · 7.5% of protein
Raw tokenHisKA:664:0.000000000000274:730:68:64
4 HATPase_c#4
774-880 aa · 107 aa · 12.0% of protein
Raw tokenHATPase_c:774:8.67e-31:880:107:109
  • Raw architecture: KdpD:21:4.38e-143:230:210:210#GAF_3:527:0.00000000000403:644:130:129#HisKA:664:0.000000000000274:730:68:64#HATPase_c:774:8.67e-31:880:107:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000017985::NC_012967.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span703151-706509Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECB_00652RefSeq proteinWP_001301349.1
Context group IDGCF_000017985::NC_012967.1::G00005
Context members
ECB_RS03435ECB_RS03440
Partner locus tags
ECB_RS03435ECB_RS03440
Partner old locus tags
ECB_00651ECB_00652
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001301349.1Primary protein accession used for annex mappings.
UniProt accessionA0A1V0MR34Primary UniProt accession resolved in the annex database.
UniProt IDA0A1V0MR34_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECB_RS03440Primary locus identifier stored in the genes table.
Old locus tagECB_00652Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_012967.1Sequence record reported by the local genomic context database.
Genomic interval703 825-706 509 nt2 685 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span703 151-706 509 ntGCF_000017985::NC_012967.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000017985::NC_012967.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_012967.1All displayed genes belong to this local TCS context.
Neighborhood span703 151-706 509 nt3 359 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
703 151 nt706 509 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECB_RS03435GCF_000017985#ECB_RS03435
RROmpR

703 151-703 828 nt · Reverse (-)

Old locus ECB_00651RefSeq WP_000186074.1
ECB_RS03440GCF_000017985#ECB_RS03440
HKClassicCurrent focus

703 825-706 509 nt · Reverse (-)

Old locus ECB_00652RefSeq WP_001301349.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0419540Run 6 · HK · 1094 sequences
Representative sequenceGCF_000009565#B21_RS03350Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + GAF_3 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0419540

Simplified PFAM architecture for HKOC_0419540

PFAM domain coverage: 607 / 894 aa (67.9%)

1 aa894 aa
KdpD: 22-230 aaKdpDDUF4118: 403-508 aaDUF4118GAF_3: 527-644 aaGAF_3HisKA: 664-730 aaHisKAHATPase_c: 776-882 aaHATPase_c
KdpDDUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[403-508] | GAF_3[527-644] | HisKA[664-730] | HATPase_c[776-882]
  • Domain count: 5
  • Matched identifier: HKOC_0419540
  • Positioned domains: KdpD 22-230 ; DUF4118 403-508 ; GAF_3 527-644 ; HisKA 664-730 ; HATPase_c 776-882
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009565#B21_RS03350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 413 997 · GCF_000017985
AssemblyASM1798v1 · Complete Genomehaploid
Genome composition4 629 812 bp · 51,0% GCEscherichia coli B str. REL606
Signal transduction countsGenes 58 · HK 28 · RR 30CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key