Gene detail

ECHS_RS13370

Histidine kinase, Classic

Escherichia coli HS · GCF_000017765

ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000017765#ECHS_RS13370Stable P2CS identifier used across views.
GenomeGCF_000017765Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1664371Run 6 · 106 sequences · id 100% · cov 80% · representative
External referencesWP_012135947.1 · A0A6G4BX07 · MIST4 ECHS_RS13370RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 475 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
HAMP: 175-243 aa (69 aa)1HisKA: 249-316 aa (68 aa)2HATPase_c: 362-469 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
175-243 aa · 69 aa · 14.5% of protein
Raw tokenHAMP:175:0.000000392:243:69:69
2 HisKA#2
249-316 aa · 68 aa · 14.3% of protein
Raw tokenHisKA:249:0.0000000000000148:316:68:64
3 HATPase_c#3
362-469 aa · 108 aa · 22.7% of protein
Raw tokenHATPase_c:362:1.59e-23:469:108:109
  • Raw architecture: HAMP:175:0.000000392:243:69:69#HisKA:249:0.0000000000000148:316:68:64#HATPase_c:362:1.59e-23:469:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000017765::NC_009800.1::G00026
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2728005-2729432Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEcHS_A2709RefSeq proteinWP_012135947.1
Context group IDGCF_000017765::NC_009800.1::G00026
Context members
ECHS_RS13370
Partner locus tags
ECHS_RS13370
Partner old locus tags
EcHS_A2709
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012135947.1Primary protein accession used for annex mappings.
UniProt accessionA0A6G4BX07Primary UniProt accession resolved in the annex database.
UniProt IDA0A6G4BX07_ECOLXDisplay identifier provided by UniProt.
GO / PubMed6 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECHS_RS13370Primary locus identifier stored in the genes table.
Old locus tagEcHS_A2709Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_009800.1Sequence record reported by the local genomic context database.
Genomic interval2 728 005-2 729 432 nt1 428 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 728 005-2 729 432 ntGCF_000017765::NC_009800.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000017765::NC_009800.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_009800.1All displayed genes belong to this local TCS context.
Neighborhood span2 728 005-2 729 432 nt1 428 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 728 005 nt2 729 432 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

ECHS_RS13370GCF_000017765#ECHS_RS13370
HKClassicCurrent focus

2 728 005-2 729 432 nt · Reverse (-)

Old locus EcHS_A2709RefSeq WP_012135947.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1664371Run 6 · HK · 106 sequences
Representative sequenceGCF_000017765#ECHS_RS13370The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1664371

Simplified PFAM architecture for HKOC_1664371

PFAM domain coverage: 229 / 475 aa (48.2%)

1 aa475 aa
HAMP: 192-244 aaHAMPHisKA: 250-316 aaHisKAHATPase_c: 362-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[192-244] | HisKA[250-316] | HATPase_c[362-470]
  • Domain count: 3
  • Matched identifier: HKOC_1664371
  • Positioned domains: HAMP 192-244 ; HisKA 250-316 ; HATPase_c 362-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_000017765#ECHS_RS13370

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 331 112 · GCF_000017765
AssemblyASM1776v1 · Complete Genomehaploid
Genome composition4 643 538 bp · 51,0% GCEscherichia coli HS
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key