Gene detail

ECSE_RS08950

Histidine kinase, Classic

Escherichia coli SE11 · GCF_000010385

ClassHKTypeClassicLength433 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000010385#ECSE_RS08950Stable P2CS identifier used across views.
GenomeGCF_000010385Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2003103Run 6 · 6279 sequences · id 100% · cov 80%
External referencesWP_000732497.1 · A0A8E0KWC0 · MIST4 ECSE_RS08950RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length433 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 433 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa433 aa
HAMP: 140-207 aa (68 aa)1HisKA: 211-269 aa (59 aa)2HATPase_c: 316-423 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
140-207 aa · 68 aa · 15.7% of protein
Raw tokenHAMP:140:0.0000000805:207:72:69
2 HisKA#2
211-269 aa · 59 aa · 13.6% of protein
Raw tokenHisKA:211:0.000000000343:269:62:64
3 HATPase_c#3
316-423 aa · 108 aa · 24.9% of protein
Raw tokenHATPase_c:316:1.91e-29:423:109:109
  • Raw architecture: HAMP:140:0.0000000805:207:72:69#HisKA:211:0.000000000343:269:62:64#HATPase_c:316:1.91e-29:423:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000010385::NC_011415.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1815662-1817686Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECSE_1730RefSeq proteinWP_000732497.1
Context group IDGCF_000010385::NC_011415.1::G00011
Context members
ECSE_RS08945ECSE_RS08950
Partner locus tags
ECSE_RS08945ECSE_RS08950
Partner old locus tags
ECSE_1729ECSE_1730
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000732497.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KWC0Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KWC0_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECSE_RS08950Primary locus identifier stored in the genes table.
Old locus tagECSE_1730Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_011415.1Sequence record reported by the local genomic context database.
Genomic interval1 816 385-1 817 686 nt1 302 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 815 662-1 817 686 ntGCF_000010385::NC_011415.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000010385::NC_011415.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_011415.1All displayed genes belong to this local TCS context.
Neighborhood span1 815 662-1 817 686 nt2 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 815 662 nt1 817 686 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECSE_RS08945GCF_000010385#ECSE_RS08945
RROmpR

1 815 662-1 816 381 nt · Forward (+)

Old locus ECSE_1729RefSeq WP_001092519.1
ECSE_RS08950GCF_000010385#ECSE_RS08950
HKClassicCurrent focus

1 816 385-1 817 686 nt · Forward (+)

Old locus ECSE_1730RefSeq WP_000732497.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2003103Run 6 · HK · 6279 sequences
Representative sequenceGCF_009909855#FNZ41_RS19465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2003103

Simplified PFAM architecture for HKOC_2003103

PFAM domain coverage: 209 / 447 aa (46.8%)

1 aa447 aa
HAMP: 163-206 aaHAMPHisKA: 212-270 aaHisKAHATPase_c: 318-423 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[163-206] | HisKA[212-270] | HATPase_c[318-423]
  • Domain count: 3
  • Matched identifier: HKOC_2003103
  • Positioned domains: HAMP 163-206 ; HisKA 212-270 ; HATPase_c 318-423
Cluster members and taxonomy
Visualization

Representative gene: GCF_009909855#FNZ41_RS19465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 409 438 · GCF_000010385
AssemblyASM1038v1 · Complete Genomehaploid
Genome composition5 155 626 bp · 50,5% GCEscherichia coli SE11
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key