Gene detail

CD630_RS15165

Histidine kinase, Classic

Clostridioides difficile 630 · GCF_000009205

ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000009205#CD630_RS15165Stable P2CS identifier used across views.
GenomeGCF_000009205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1468136Run 6 · 153 sequences · id 100% · cov 80% · representative
External referencesWP_011861709.1 · Q183S5 · MIST4 CD630_RS15165RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
His_kinase: 305-376 aa (72 aa)1HATPase_c: 396-496 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw tokenHis_kinase:305:1.21e-24:376:72:80
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw tokenHATPase_c:396:0.00000286:496:107:109
  • Raw architecture: His_kinase:305:1.21e-24:376:72:80#HATPase_c:396:0.00000286:496:107:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000009205::NC_009089.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3317366-3319683Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCD630_28390RefSeq proteinWP_011861709.1
Context group IDGCF_000009205::NC_009089.1::G00050
Context members
CD630_RS15160CD630_RS15165
Partner locus tags
CD630_RS15160CD630_RS15165
Partner old locus tags
CD630_28380CD630_28390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_011861709.1Primary protein accession used for annex mappings.
UniProt accessionQ183S5Primary UniProt accession resolved in the annex database.
UniProt IDQ183S5_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCD630_RS15165Primary locus identifier stored in the genes table.
Old locus tagCD630_28390Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_009089.1Sequence record reported by the local genomic context database.
Genomic interval3 318 178-3 319 683 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 317 366-3 319 683 ntGCF_000009205::NC_009089.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000009205::NC_009089.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_009089.1All displayed genes belong to this local TCS context.
Neighborhood span3 317 366-3 319 683 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 317 366 nt3 319 683 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CD630_RS15160GCF_000009205#CD630_RS15160
RRunclassified

3 317 366-3 318 064 nt · Reverse (-)

Old locus CD630_28380RefSeq WP_003436119.1
CD630_RS15165GCF_000009205#CD630_RS15165
HKClassicCurrent focus

3 318 178-3 319 683 nt · Reverse (-)

Old locus CD630_28390RefSeq WP_011861709.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1468136Run 6 · HK · 153 sequences
Representative sequenceGCF_000009205#CD630_RS15165The current gene is the representative for this cluster.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1468136

Simplified PFAM architecture for HKOC_1468136

PFAM domain coverage: 137 / 501 aa (27.3%)

1 aa501 aa
Cupin_2: 34-96 aaCupin_2His_kinase: 303-376 aaHis_kinase
Cupin_2His_kinase
  • Simplified architecture: Cupin_2 + His_kinase
  • Raw architecture: Cupin_2[34-96] | His_kinase[303-376]
  • Domain count: 2
  • Matched identifier: HKOC_1468136
  • Positioned domains: Cupin_2 34-96 ; His_kinase 303-376
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS15165

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 153 total members. Page 1 / 4.

GCF_000009205#CD630_RS15165 (representative)
CD630_RS15165 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000448725#QAW_RS15080
QAW_RS15080 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000448885#QAU_RS14690
QAU_RS14690 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000449085#QCM_RS14150
QCM_RS14150 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000450565#QMA_RS14580
QMA_RS14580 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000451085#QSE_RS15665
QSE_RS15665 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000451105#QSG_RS15890
QSG_RS15890 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000451185#QQ3_RS14975
QQ3_RS14975 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000451805#QSQ_RS03920
QSQ_RS03920 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000451825#QSU_RS04200
QSU_RS04200 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000530595#BN185_RS14270
BN185_RS14270 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000530695#BN188_RS14350
BN188_RS14350 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000531225#BN184_RS14700
BN184_RS14700 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000828225#SE46_RS06020
SE46_RS06020 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000828235#SE44_RS08470
SE44_RS08470 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000828255#SE45_RS04280
SE45_RS04280 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000828325#NX98_RS07145
NX98_RS07145 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000932055#CDIF630_RS15575
CDIF630_RS15575 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_000953275#CD630DERM_RS15240
CD630DERM_RS15240 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_001757615#BM72_RS07080
BM72_RS07080 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_001971905#BER39_RS14895
BER39_RS14895 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002080065#CDIF630erm_RS15460
CDIF630erm_RS15460 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002082945#A6J96_RS19610
A6J96_RS19610 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002300915#BGT99_RS05725
BGT99_RS05725 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002300955#BGU00_RS02495
BGU00_RS02495 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002301595#BGU31_RS02580
BGU31_RS02580 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002302085#BGU87_RS02675
BGU87_RS02675 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002303575#BGU68_RS19435
BGU68_RS19435 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002304575#BGU17_RS09070
BGU17_RS09070 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_002940905#AWN78_RS20085
AWN78_RS20085 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_003313565#CDIF27639_RS15270
CDIF27639_RS15270 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_003862575#EGM15_RS02825
EGM15_RS02825 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_003863305#EGL80_RS05720
EGL80_RS05720 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_003932635#EGL77_RS09775
EGL77_RS09775 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004315105#E0O87_RS04775
E0O87_RS04775 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004315445#E0P59_RS04700
E0P59_RS04700 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004316085#E0P76_RS01915
E0P76_RS01915 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004316465#E0P94_RS01070
E0P94_RS01070 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004316605#E0Q05_RS01700
E0Q05_RS01700 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004318185#E0Q92_RS16270
E0Q92_RS16270 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004318605#E0R01_RS01465
E0R01_RS01465 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004319345#E0R39_RS12185
E0R39_RS12185 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004319885#E0R96_RS18350
E0R96_RS18350 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004684515#E5F39_RS16410
E5F39_RS16410 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_004684665#E5F32_RS17860
E5F32_RS17860 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_006381045#DA429_RS16035
DA429_RS16035 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_006408335#DA411_RS16200
DA411_RS16200 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_007001945#EWL97_RS01515
EWL97_RS01515 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_007001975#EWL98_RS01515
EWL98_RS01515 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5
GCF_007002025#EWL95_RS01515
EWL95_RS01515 · HK · Classic
RefSeq: WP_011861709.1
UniProt: Q183S5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 272 563 · GCF_000009205
AssemblyASM920v2 · Complete Genomehaploid
Genome composition4 298 133 bp · 29,0% GCClostridioides difficile 630
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key