1 Response_reg#1
4-117 aa · 114 aa · 32.5% of protein
Raw token
Response_reg:4:3.57e-20:117:115:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C_RS21450
Response regulator, unclassified
Escherichia coli CFT073 · GCF_000007445
ClassRRTypeunclassifiedLength351 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007445#C_RS21450Stable P2CS identifier used across views.
GenomeGCF_000007445Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length351 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage192 / 351 aa (54.7%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa351 aa
Domain-by-domain annotation3 items
2 HTH_AraC#2
252-292 aa · 41 aa · 11.7% of protein
Raw token
HTH_AraC:252:0.0000000239:292:41:423 HTH_AraC#3
307-343 aa · 37 aa · 10.5% of protein
Raw token
HTH_AraC:307:0.00000000943:343:37:42- Raw architecture: Response_reg:4:3.57e-20:117:115:111#HTH_AraC:252:0.0000000239:292:41:42#HTH_AraC:307:0.00000000943:343:37:42
- Domain description: 1 Response_reg,2 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007445::NC_004431.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4322181-4324515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagc4546RefSeq proteinWP_000494233.1
Context group ID
GCF_000007445::NC_004431.1::G00030Context members
C_RS21445C_RS21450
Partner locus tags
C_RS21445C_RS21450
Partner old locus tags
c4545c4546
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000494233.1Primary protein accession used for annex mappings.
UniProt accessionB7MZF9Primary UniProt accession resolved in the annex database.
UniProt IDB7MZF9_ECO81Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC_RS21450Primary locus identifier stored in the genes table.
Old locus tagc4546Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004431.1Sequence record reported by the local genomic context database.
Genomic interval4 323 460-4 324 515 nt1 056 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 322 181-4 324 515 ntGCF_000007445::NC_004431.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007445::NC_004431.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004431.1All displayed genes belong to this local TCS context.
Neighborhood span4 322 181-4 324 515 nt2 335 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 322 181 nt4 324 515 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS21450The current gene is the representative for this cluster.
PFAM architectureResponse_reg + HTH_AraC + HTH_AraC3 domains in the representative PFAM annotation.
PFAM architecture for RROC_0477581
Simplified PFAM architecture for RROC_0477581
PFAM domain coverage: 190 / 351 aa (54.1%)
1 aa351 aa
Response_regHTH_AraCHTH_AraC
- Simplified architecture: Response_reg + HTH_AraC + HTH_AraC
- Raw architecture: Response_reg[4-116] | HTH_AraC[252-292] | HTH_AraC[308-343]
- Domain count: 3
- Matched identifier: RROC_0477581
- Positioned domains: Response_reg 4-116 ; Response_reg 4-116 ; HTH_AraC 252-292 ; HTH_AraC 252-292 ; HTH_AraC 308-343 ; HTH_AraC 308-343
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS21450
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 199 310 · GCF_000007445
AssemblyASM744v1 · Complete Genomehaploid
Genome composition5 231 428 bp · 50,5% GCEscherichia coli CFT073
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key