1 PocR#1
20-183 aa · 164 aa · 39.0% of protein
Raw token
PocR:20:2.63e-54:183:164:162P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C_RS21445
Histidine kinase, Classic
Escherichia coli CFT073 · GCF_000007445
ClassHKTypeClassicLength420 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007445#C_RS21445Stable P2CS identifier used across views.
GenomeGCF_000007445Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PocRHis_kinaseHATPase_c
Protein length420 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage353 / 420 aa (84.0%)Merged over positioned domains only.
Domain description1 PocR,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa420 aa
Domain-by-domain annotation3 items
2 His_kinase#2
215-295 aa · 81 aa · 19.3% of protein
Raw token
His_kinase:215:6.98e-33:295:81:803 HATPase_c#3
312-419 aa · 108 aa · 25.7% of protein
Raw token
HATPase_c:312:0.0000000629:419:113:109- Raw architecture: PocR:20:2.63e-54:183:164:162#His_kinase:215:6.98e-33:295:81:80#HATPase_c:312:0.0000000629:419:113:109
- Domain description: 1 PocR,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007445::NC_004431.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4322181-4324515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagc4545RefSeq proteinWP_011076674.1
Context group ID
GCF_000007445::NC_004431.1::G00030Context members
C_RS21445C_RS21450
Partner locus tags
C_RS21445C_RS21450
Partner old locus tags
c4545c4546
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011076674.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2VCB9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2VCB9_ECOL6Display identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC_RS21445Primary locus identifier stored in the genes table.
Old locus tagc4545Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004431.1Sequence record reported by the local genomic context database.
Genomic interval4 322 181-4 323 443 nt1 263 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 322 181-4 324 515 ntGCF_000007445::NC_004431.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007445::NC_004431.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004431.1All displayed genes belong to this local TCS context.
Neighborhood span4 322 181-4 324 515 nt2 335 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 322 181 nt4 324 515 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS21445The current gene is the representative for this cluster.
PFAM architecturePocR + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2267260
Simplified PFAM architecture for HKOC_2267260
PFAM domain coverage: 350 / 420 aa (83.3%)
1 aa420 aa
PocRHis_kinaseHATPase_c
- Simplified architecture: PocR + His_kinase + HATPase_c
- Raw architecture: PocR[20-182] | His_kinase[215-295] | HATPase_c[313-418]
- Domain count: 3
- Matched identifier: HKOC_2267260
- Positioned domains: PocR 20-182 ; His_kinase 215-295 ; HATPase_c 313-418
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS21445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 199 310 · GCF_000007445
AssemblyASM744v1 · Complete Genomehaploid
Genome composition5 231 428 bp · 50,5% GCEscherichia coli CFT073
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key