1 PilJ#1
31-125 aa · 95 aa · 16.8% of protein
Raw token
PilJ:31:3.53e-17:125:111:112P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C_RS14225
Histidine kinase, Classic
Escherichia coli CFT073 · GCF_000007445
ClassHKTypeClassicLength566 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000007445#C_RS14225Stable P2CS identifier used across views.
GenomeGCF_000007445Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PilJHAMPHisKA_3HATPase_c
Protein length566 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage324 / 566 aa (57.2%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa566 aa
Domain-by-domain annotation4 items
2 HAMP#2
150-224 aa · 75 aa · 13.3% of protein
Raw token
HAMP:150:0.00000000000132:224:75:693 HisKA_3#3
361-424 aa · 64 aa · 11.3% of protein
Raw token
HisKA_3:361:2.31e-17:424:64:684 HATPase_c#4
467-556 aa · 90 aa · 15.9% of protein
Raw token
HATPase_c:467:2.11e-19:556:105:109- Raw architecture: PilJ:31:3.53e-17:125:111:112#HAMP:150:0.00000000000132:224:75:69#HisKA_3:361:2.31e-17:424:64:68#HATPase_c:467:2.11e-19:556:105:109
- Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000007445::NC_004431.1::G00022
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2856497-2858197Genomic interval covered by the local TCS group.
Identifiers
Old locus tagc2996RefSeq proteinWP_001296285.1
Context group ID
GCF_000007445::NC_004431.1::G00022Context members
C_RS14225
Partner locus tags
C_RS14225
Partner old locus tags
c2996
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001296285.1Primary protein accession used for annex mappings.
UniProt accessionD3H2W0Primary UniProt accession resolved in the annex database.
UniProt IDD3H2W0_ECO44Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC_RS14225Primary locus identifier stored in the genes table.
Old locus tagc2996Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004431.1Sequence record reported by the local genomic context database.
Genomic interval2 856 497-2 858 197 nt1 701 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 856 497-2 858 197 ntGCF_000007445::NC_004431.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007445::NC_004431.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004431.1All displayed genes belong to this local TCS context.
Neighborhood span2 856 497-2 858 197 nt1 701 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 856 497 nt2 858 197 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
C_RS14225GCF_000007445#C_RS14225
HKClassicCurrent focus
2 856 497-2 858 197 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS14225The current gene is the representative for this cluster.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1228913
Simplified PFAM architecture for HKOC_1228913
PFAM domain coverage: 302 / 566 aa (53.4%)
1 aa566 aa
PilJHAMPHisKA_3HATPase_c
- Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
- Raw architecture: PilJ[32-127] | HAMP[172-223] | HisKA_3[361-424] | HATPase_c[467-556]
- Domain count: 4
- Matched identifier: HKOC_1228913
- Positioned domains: PilJ 32-127 ; HAMP 172-223 ; HisKA_3 361-424 ; HATPase_c 467-556
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS14225
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 199 310 · GCF_000007445
AssemblyASM744v1 · Complete Genomehaploid
Genome composition5 231 428 bp · 50,5% GCEscherichia coli CFT073
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key