1 Response_reg#1
7-117 aa · 111 aa · 46.4% of protein
Raw token
Response_reg:7:1.02e-38:117:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS22650
Response regulator OmpR family
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassRRTypeOmpRLength239 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007405#S_RS22650Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length239 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage188 / 239 aa (78.7%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa239 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
156-232 aa · 77 aa · 32.2% of protein
Raw token
Trans_reg_C:156:1.36e-28:232:77:77- Raw architecture: Response_reg:7:1.02e-38:117:111:111#Trans_reg_C:156:1.36e-28:232:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007405::NC_004741.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4266806-4268874Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS4339%2CS_4339RefSeq proteinWP_001157751.1
Context group ID
GCF_000007405::NC_004741.1::G00031Context members
S_RS22650S_RS22655
Partner locus tags
S_RS22650S_RS22655
Partner old locus tags
S4339%2CS_4339S4340%2CS_4340
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001157751.1Primary protein accession used for annex mappings.
UniProt accessionA0ABX7MJD9Primary UniProt accession resolved in the annex database.
UniProt IDA0ABX7MJD9_ERWAMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS22650Primary locus identifier stored in the genes table.
Old locus tagS4339%2CS_4339Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval4 266 806-4 267 525 nt720 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 266 806-4 268 874 ntGCF_000007405::NC_004741.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span4 266 806-4 268 874 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 266 806 nt4 268 874 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000459135#G856_RS05680Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0626681
Simplified PFAM architecture for RROC_0626681
PFAM domain coverage: 187 / 266 aa (70.3%)
1 aa266 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[7-117] | Trans_reg_C[157-232]
- Domain count: 2
- Matched identifier: RROC_0626681
- Positioned domains: Response_reg 7-117 ; Response_reg 7-117 ; Trans_reg_C 157-232 ; Trans_reg_C 157-232
Cluster members and taxonomy
Representative gene: GCF_000459135#G856_RS05680
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key