1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw token
HisKA:237:0.00000000000108:299:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS19085
Histidine kinase, Classic
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007405#S_RS19085Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw token
HATPase_c:345:6.45e-34:451:110:109- Raw architecture: HisKA:237:0.00000000000108:299:63:64#HATPase_c:345:6.45e-34:451:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007405::NC_004741.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3549614-3552312Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS3660%2CS_3660RefSeq proteinWP_001211933.1
Context group ID
GCF_000007405::NC_004741.1::G00027Context members
S_RS19080S_RS19085
Partner locus tags
S_RS19080S_RS19085
Partner old locus tags
S3659%2CS_3659S3660%2CS_3660
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211933.1Primary protein accession used for annex mappings.
UniProt accessionA0AB36PK82Primary UniProt accession resolved in the annex database.
UniProt IDA0AB36PK82_SHIFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS19085Primary locus identifier stored in the genes table.
Old locus tagS3660%2CS_3660Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval3 550 936-3 552 312 nt1 377 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 549 614-3 552 312 ntGCF_000007405::NC_004741.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span3 549 614-3 552 312 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 549 614 nt3 552 312 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858251
Simplified PFAM architecture for HKOC_1858251
PFAM domain coverage: 168 / 458 aa (36.7%)
1 aa458 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[238-300] | HATPase_c[346-450]
- Domain count: 2
- Matched identifier: HKOC_1858251
- Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Representative gene: GCF_000006925#SF4075
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key