1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw token
HAMP:72:0.00000092:139:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS18850
Histidine kinase, Classic
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007405#S_RS18850Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
Domain-by-domain annotation3 items
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw token
HisKA:147:0.00000000186:204:61:643 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw token
HATPase_c:252:7.61e-22:360:111:109- Raw architecture: HAMP:72:0.00000092:139:68:69#HisKA:147:0.00000000186:204:61:64#HATPase_c:252:7.61e-22:360:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007405::NC_004741.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3495795-3497564Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS3619%2CS_3619RefSeq proteinWP_001052137.1
Context group ID
GCF_000007405::NC_004741.1::G00025Context members
S_RS18850S_RS18855
Partner locus tags
S_RS18850S_RS18855
Partner old locus tags
S3619%2CS_3619S3620%2CS_3620
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001052137.1Primary protein accession used for annex mappings.
UniProt accessionQ8XDU5Primary UniProt accession resolved in the annex database.
UniProt IDQ8XDU5_ECO57Display identifier provided by UniProt.
GO / PubMed3 / 2Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS18850Primary locus identifier stored in the genes table.
Old locus tagS3619%2CS_3619Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval3 495 795-3 496 895 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 495 795-3 497 564 ntGCF_000007405::NC_004741.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span3 495 795-3 497 564 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 495 795 nt3 497 564 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006665#Z_RS26735Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2711907
Simplified PFAM architecture for HKOC_2711907
PFAM domain coverage: 165 / 366 aa (45.1%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-203] | HATPase_c[252-359]
- Domain count: 2
- Matched identifier: HKOC_2711907
- Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Representative gene: GCF_000006665#Z_RS26735
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key