1 HisKA#1
469-534 aa · 66 aa · 7.0% of protein
Raw token
HisKA:469:2.47e-17:534:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS12820
Histidine kinase, Hybrid
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassHKTypeHybridLength949 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000007405#S_RS12820Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length949 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage286 / 949 aa (30.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa949 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
581-690 aa · 110 aa · 11.6% of protein
Raw token
HATPase_c:581:7.7e-39:690:110:1093 Response_reg#3
827-936 aa · 110 aa · 11.6% of protein
Raw token
Response_reg:827:3.63e-36:936:110:111- Raw architecture: HisKA:469:2.47e-17:534:66:64#HATPase_c:581:7.7e-39:690:110:109#Response_reg:827:3.63e-36:936:110:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000007405::NC_004741.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2317887-2320736Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS2433%2CS_2433RefSeq proteinWP_000875997.1
Context group ID
GCF_000007405::NC_004741.1::G00017Context members
S_RS12820
Partner locus tags
S_RS12820
Partner old locus tags
S2433%2CS_2433
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000875997.1Primary protein accession used for annex mappings.
UniProt accessionA0AB36PFX0Primary UniProt accession resolved in the annex database.
UniProt IDA0AB36PFX0_SHIFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS12820Primary locus identifier stored in the genes table.
Old locus tagS2433%2CS_2433Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval2 317 887-2 320 736 nt2 850 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 317 887-2 320 736 ntGCF_000007405::NC_004741.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span2 317 887-2 320 736 nt2 850 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 317 887 nt2 320 736 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
S_RS12820GCF_000007405#S_RS12820
HKHybridCurrent focus
2 317 887-2 320 736 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007405#S_RS12820The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + RcsC + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0327674
Simplified PFAM architecture for HKOC_0327674
PFAM domain coverage: 376 / 949 aa (39.6%)
1 aa949 aa
HisKAHATPase_cRcsCResponse_reg
- Simplified architecture: HisKA + HATPase_c + RcsC + Response_reg
- Raw architecture: HisKA[470-534] | HATPase_c[581-690] | RcsC[709-799] | Response_reg[827-936]
- Domain count: 4
- Matched identifier: HKOC_0327674
- Positioned domains: HisKA 470-534 ; HATPase_c 581-690 ; RcsC 709-799 ; Response_reg 827-936
Cluster members and taxonomy
Representative gene: GCF_000007405#S_RS12820
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key