1 Response_reg#1
3-112 aa · 110 aa · 49.3% of protein
Raw token
Response_reg:3:1.06e-32:112:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS11170
Response regulator OmpR family
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassRRTypeOmpRLength223 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007405#S_RS11170Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length223 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 223 aa (82.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa223 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
146-218 aa · 73 aa · 32.7% of protein
Raw token
Trans_reg_C:146:3.21e-30:218:74:77- Raw architecture: Response_reg:3:1.06e-32:112:111:111#Trans_reg_C:146:3.21e-30:218:74:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007405::NC_004741.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2015585-2017614Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS2113%2CS_2113RefSeq proteinWP_001347103.1
Context group ID
GCF_000007405::NC_004741.1::G00012Context members
S_RS11165S_RS11170
Partner locus tags
S_RS11165S_RS11170
Partner old locus tags
S2112%2CS_2112S2113%2CS_2113
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001347103.1Primary protein accession used for annex mappings.
UniProt accessionA0A4P7TTK9Primary UniProt accession resolved in the annex database.
UniProt IDA0A4P7TTK9_SHIFMDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS11170Primary locus identifier stored in the genes table.
Old locus tagS2113%2CS_2113Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval2 016 943-2 017 614 nt672 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 015 585-2 017 614 ntGCF_000007405::NC_004741.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span2 015 585-2 017 614 nt2 030 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 015 585 nt2 017 614 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1586806
Simplified PFAM architecture for RROC_1586806
PFAM domain coverage: 183 / 223 aa (82.1%)
1 aa223 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[3-112] | Trans_reg_C[146-218]
- Domain count: 2
- Matched identifier: RROC_1586806
- Positioned domains: Response_reg 3-112 ; Response_reg 3-112 ; Trans_reg_C 146-218 ; Trans_reg_C 146-218
Cluster members and taxonomy
Representative gene: GCF_000006925#SF2016
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key