1 Response_reg#1
6-108 aa · 103 aa · 29.5% of protein
Raw token
Response_reg:6:7.85e-27:108:105:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS10690
Response regulator, CheB family
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassRRTypeCheBLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007405#S_RS10690Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
Response_regCheB_methylest
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage282 / 349 aa (80.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation2 items
2 CheB_methylest#2
159-337 aa · 179 aa · 51.3% of protein
Raw token
CheB_methylest:159:3.79e-91:337:180:177- Raw architecture: Response_reg:6:7.85e-27:108:105:111#CheB_methylest:159:3.79e-91:337:180:177
- Domain description: 1 Response_reg,1 CheB_methylest
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007405::NC_004741.1::G00009
Group size22 locus tags listed below.
HK / RR0 / 2Counts resolved for the local TCS neighborhood.
Context span1942332-1943785Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS2023%2CS_2023RefSeq proteinWP_000036372.1
Context group ID
GCF_000007405::NC_004741.1::G00009Context members
S_RS10685S_RS10690
Partner locus tags
S_RS10685S_RS10690
Partner old locus tags
S2022%2CS_2022S2023%2CS_2023
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000036372.1Primary protein accession used for annex mappings.
UniProt accessionQ0T3N7Primary UniProt accession resolved in the annex database.
UniProt IDQ0T3N7_SHIF8Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS10690Primary locus identifier stored in the genes table.
Old locus tagS2023%2CS_2023Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval1 942 736-1 943 785 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 942 332-1 943 785 ntGCF_000007405::NC_004741.1::G00009
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00009Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span1 942 332-1 943 785 nt1 454 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 942 332 nt1 943 785 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0481946
Simplified PFAM architecture for RROC_0481946
PFAM domain coverage: 281 / 349 aa (80.5%)
1 aa349 aa
Response_regCheB_methylest
- Simplified architecture: Response_reg + CheB_methylest
- Raw architecture: Response_reg[6-108] | CheB_methylest[159-336]
- Domain count: 2
- Matched identifier: RROC_0481946
- Positioned domains: Response_reg 6-108 ; Response_reg 6-108 ; CheB_methylest 159-336 ; CheB_methylest 159-336
Cluster members and taxonomy
Representative gene: GCF_000006925#SF1932
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key