1 HAMP#1
140-207 aa · 68 aa · 15.7% of protein
Raw token
HAMP:140:0.0000000836:207:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
S_RS09295
Histidine kinase, Classic
Shigella flexneri 2a str. 2457T · GCF_000007405
ClassHKTypeClassicLength433 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000007405#S_RS09295Stable P2CS identifier used across views.
GenomeGCF_000007405Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length433 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 433 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa433 aa
Domain-by-domain annotation3 items
2 HisKA#2
211-269 aa · 59 aa · 13.6% of protein
Raw token
HisKA:211:0.000000000379:269:62:643 HATPase_c#3
316-423 aa · 108 aa · 24.9% of protein
Raw token
HATPase_c:316:9.81e-29:423:109:109- Raw architecture: HAMP:140:0.0000000836:207:72:69#HisKA:211:0.000000000379:269:62:64#HATPase_c:316:9.81e-29:423:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000007405::NC_004741.1::G00008
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1698900-1700201Genomic interval covered by the local TCS group.
Identifiers
Old locus tagS1763%2CS_1763RefSeq proteinWP_000732493.1
Context group ID
GCF_000007405::NC_004741.1::G00008Context members
S_RS09295
Partner locus tags
S_RS09295
Partner old locus tags
S1763%2CS_1763
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000732493.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P2IYN4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P2IYN4_SHIFLDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagS_RS09295Primary locus identifier stored in the genes table.
Old locus tagS1763%2CS_1763Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004741.1Sequence record reported by the local genomic context database.
Genomic interval1 698 900-1 700 201 nt1 302 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 698 900-1 700 201 ntGCF_000007405::NC_004741.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007405::NC_004741.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004741.1All displayed genes belong to this local TCS context.
Neighborhood span1 698 900-1 700 201 nt1 302 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 698 900 nt1 700 201 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
S_RS09295GCF_000007405#S_RS09295
HKClassicCurrent focus
1 698 900-1 700 201 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2140054
Simplified PFAM architecture for HKOC_2140054
PFAM domain coverage: 209 / 433 aa (48.3%)
1 aa433 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[163-206] | HisKA[212-270] | HATPase_c[318-423]
- Domain count: 3
- Matched identifier: HKOC_2140054
- Positioned domains: HAMP 163-206 ; HisKA 212-270 ; HATPase_c 318-423
Cluster members and taxonomy
Representative gene: GCF_000006925#SF1632
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 215 · GCF_000007405
AssemblyASM740v1 · Complete Genomehaploid
Genome composition4 599 354 bp · 51,0% GCShigella flexneri 2a str. 2457T
Signal transduction countsGenes 52 · HK 24 · RR 28CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key