1 HAMP#1
167-236 aa · 70 aa · 15.0% of protein
Raw token
HAMP:167:5.59e-16:236:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
Z_RS15240
Histidine kinase, Classic
Escherichia coli O157:H7 str. EDL933 · GCF_000006665
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006665#Z_RS15240Stable P2CS identifier used across views.
GenomeGCF_000006665Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 467 aa (53.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation3 items
2 HisKA#2
240-304 aa · 65 aa · 13.9% of protein
Raw token
HisKA:240:0.0000000000000116:304:65:643 HATPase_c#3
349-461 aa · 113 aa · 24.2% of protein
Raw token
HATPase_c:349:1.72e-29:461:113:109- Raw architecture: HAMP:167:5.59e-16:236:70:69#HisKA:240:0.0000000000000116:304:65:64#HATPase_c:349:1.72e-29:461:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000006665::NC_002655.2::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2908528-2910650Genomic interval covered by the local TCS group.
Identifiers
Old locus tagZ3247RefSeq proteinWP_000675144.1
Context group ID
GCF_000006665::NC_002655.2::G00017Context members
Z_RS15240Z_RS15245
Partner locus tags
Z_RS15240Z_RS15245
Partner old locus tags
Z3247Z3248
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000675144.1Primary protein accession used for annex mappings.
UniProt accessionD3GZE2Primary UniProt accession resolved in the annex database.
UniProt IDD3GZE2_ECO44Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagZ_RS15240Primary locus identifier stored in the genes table.
Old locus tagZ3247Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_002655.2Sequence record reported by the local genomic context database.
Genomic interval2 908 528-2 909 931 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 908 528-2 910 650 ntGCF_000006665::NC_002655.2::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006665::NC_002655.2::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_002655.2All displayed genes belong to this local TCS context.
Neighborhood span2 908 528-2 910 650 nt2 123 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 908 528 nt2 910 650 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_019295095#KYD80_RS00890Use this link to inspect the representative gene detail.
PFAM architectureMFS_1 + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0342516
Simplified PFAM architecture for HKOC_0342516
PFAM domain coverage: 620 / 938 aa (66.1%)
1 aa938 aa
MFS_1HAMPHisKAHATPase_c
- Simplified architecture: MFS_1 + HAMP + HisKA + HATPase_c
- Raw architecture: MFS_1[15-405] | HAMP[655-706] | HisKA[711-775] | HATPase_c[820-931]
- Domain count: 4
- Matched identifier: HKOC_0342516
- Positioned domains: MFS_1 15-405 ; HAMP 655-706 ; HisKA 711-775 ; HATPase_c 820-931
Cluster members and taxonomy
Representative gene: GCF_019295095#KYD80_RS00890
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 155 864 · GCF_000006665
AssemblyASM666v1 · Chromosomehaploid
Genome composition5 620 522 bp · 50,5% GCEscherichia coli O157:H7 str. EDL933
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key