1 HAMP#1
69-136 aa · 68 aa · 18.7% of protein
Raw token
HAMP:69:0.00000072:136:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b4112
Histidine kinase, Classic
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeClassicLength363 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b4112Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length363 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 363 aa (64.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa363 aa
Domain-by-domain annotation3 items
2 HisKA#2
144-201 aa · 58 aa · 16.0% of protein
Raw token
HisKA:144:0.00000000162:201:61:643 HATPase_c#3
249-357 aa · 109 aa · 30.0% of protein
Raw token
HATPase_c:249:5.44e-22:357:111:109- Raw architecture: HAMP:69:0.00000072:136:68:69#HisKA:144:0.00000000162:201:61:64#HATPase_c:249:5.44e-22:357:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000005845::NC_000913.3::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4332181-4333950Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00035Context members
b4112b4113
Partner locus tags
b4112b4113
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqNP_418536.1Primary protein accession used for annex mappings.
UniProt accessionG1E6H3Primary UniProt accession resolved in the annex database.
UniProt IDG1E6H3_ECOLIDisplay identifier provided by UniProt.
GO / PubMed3 / 10Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb4112Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval4 332 181-4 333 272 nt1 092 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 332 181-4 333 950 ntGCF_000005845::NC_000913.3::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span4 332 181-4 333 950 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 332 181 nt4 333 950 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000010245#Y75_RS21455Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2711914
Simplified PFAM architecture for HKOC_2711914
PFAM domain coverage: 165 / 366 aa (45.1%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-203] | HATPase_c[252-359]
- Domain count: 2
- Matched identifier: HKOC_2711914
- Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Representative gene: GCF_000010245#Y75_RS21455
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key