Gene detail

b4003

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b4003Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1772879Run 6 · 4703 sequences · id 100% · cov 80% · representative
External referencesNP_418431.1 · MIST4 b4003RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 465 aa (36.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
HisKA: 244-306 aa (63 aa)1HATPase_c: 352-458 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
244-306 aa · 63 aa · 13.5% of protein
Raw tokenHisKA:244:0.000000000000644:306:63:64
2 HATPase_c#2
352-458 aa · 107 aa · 23.0% of protein
Raw tokenHATPase_c:352:7.94e-34:458:110:109
  • Raw architecture: HisKA:244:0.000000000000644:306:63:64#HATPase_c:352:7.94e-34:458:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4201926-4204645Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00034
Context members
b4003b4004
Partner locus tags
b4003b4004
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_418431.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb4003Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval4 201 926-4 203 323 nt1 398 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 201 926-4 204 645 ntGCF_000005845::NC_000913.3::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span4 201 926-4 204 645 nt2 720 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 201 926 nt4 204 645 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b4003GCF_000005845#b4003
HKClassicCurrent focus

4 201 926-4 203 323 nt · Forward (+)

RefSeq NP_418431.1
b4004GCF_000005845#b4004
RRNtrC

4 203 320-4 204 645 nt · Forward (+)

RefSeq NP_418432.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1772879Run 6 · HK · 4703 sequences
Representative sequenceGCF_000005845#b4003The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1772879

Simplified PFAM architecture for HKOC_1772879

PFAM domain coverage: 168 / 465 aa (36.1%)

1 aa465 aa
HisKA: 245-307 aaHisKAHATPase_c: 353-457 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-307] | HATPase_c[353-457]
  • Domain count: 2
  • Matched identifier: HKOC_1772879
  • Positioned domains: HisKA 245-307 ; HATPase_c 353-457
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b4003

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key