1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw token
HAMP:165:0.000000000000956:234:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b3911
Histidine kinase, Classic
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b3911Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw token
HisKA:238:8.52e-17:299:63:643 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw token
HATPase_c:345:6.1e-30:453:110:109- Raw architecture: HAMP:165:0.000000000000956:234:70:69#HisKA:238:8.52e-17:299:63:64#HATPase_c:345:6.1e-30:453:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000005845::NC_000913.3::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4103602-4105670Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00033Context members
b3911b3912
Partner locus tags
b3911b3912
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_418347.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb3911Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval4 103 602-4 104 975 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 103 602-4 105 670 ntGCF_000005845::NC_000913.3::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span4 103 602-4 105 670 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 103 602 nt4 105 670 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1873333
Simplified PFAM architecture for HKOC_1873333
PFAM domain coverage: 293 / 457 aa (64.1%)
1 aa457 aa
CpxA_periHAMPHisKAHATPase_c
- Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
- Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
- Domain count: 4
- Matched identifier: HKOC_1873333
- Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Representative gene: GCF_000005845#b3911
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key