Gene detail

b3869

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b3869Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2800892Run 6 · 33394 sequences · id 100% · cov 80% · representative
External referencesNP_418305.1 · MIST4 b3869RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 349 aa (74.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
PAS: 11-99 aa (89 aa)1HisKA: 131-186 aa (56 aa)2HATPase_c: 234-349 aa (116 aa)3
Domain-by-domain annotation3 items
1 PAS#1
11-99 aa · 89 aa · 25.5% of protein
Raw tokenPAS:11:0.000000682:99:92:113
2 HisKA#2
131-186 aa · 56 aa · 16.0% of protein
Raw tokenHisKA:131:0.000000000000602:186:56:64
3 HATPase_c#3
234-349 aa · 116 aa · 33.2% of protein
Raw tokenHATPase_c:234:4.56e-24:349:120:109
  • Raw architecture: PAS:11:0.000000682:99:92:113#HisKA:131:0.000000000000602:186:56:64#HATPase_c:234:4.56e-24:349:120:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4053869-4056339Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00032
Context members
b3868b3869
Partner locus tags
b3868b3869
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_418305.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb3869Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval4 055 290-4 056 339 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 053 869-4 056 339 ntGCF_000005845::NC_000913.3::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span4 053 869-4 056 339 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 053 869 nt4 056 339 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b3868GCF_000005845#b3868
RRNtrC

4 053 869-4 055 278 nt · Reverse (-)

RefSeq NP_418304.1
b3869GCF_000005845#b3869
HKClassicCurrent focus

4 055 290-4 056 339 nt · Reverse (-)

RefSeq NP_418305.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2800892Run 6 · HK · 33394 sequences
Representative sequenceGCF_000005845#b3869The current gene is the representative for this cluster.
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2800892

Simplified PFAM architecture for HKOC_2800892

PFAM domain coverage: 260 / 349 aa (74.5%)

1 aa349 aa
PAS: 11-99 aaPASHisKA: 131-186 aaHisKAHATPase_c: 234-348 aaHATPase_c
PASHisKAHATPase_c
  • Simplified architecture: PAS + HisKA + HATPase_c
  • Raw architecture: PAS[11-99] | HisKA[131-186] | HATPase_c[234-348]
  • Domain count: 3
  • Matched identifier: HKOC_2800892
  • Positioned domains: PAS 11-99 ; HisKA 131-186 ; HATPase_c 234-348
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b3869

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key