1 Response_reg#1
6-116 aa · 111 aa · 23.7% of protein
Raw token
Response_reg:6:7.31e-39:116:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b3868
Response regulator NtrC family
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassRRTypeNtrCLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b3868Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regAAA_5HTH_8
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage270 / 469 aa (57.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 AAA_5#2
163-281 aa · 119 aa · 25.4% of protein
Raw token
AAA_5:163:0.0000000627:281:128:1353 HTH_8#3
427-466 aa · 40 aa · 8.5% of protein
Raw token
HTH_8:427:0.0000000000000167:466:40:40- Raw architecture: Response_reg:6:7.31e-39:116:111:111#AAA_5:163:0.0000000627:281:128:135#HTH_8:427:0.0000000000000167:466:40:40
- Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000005845::NC_000913.3::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4053869-4056339Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00032Context members
b3868b3869
Partner locus tags
b3868b3869
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_418304.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb3868Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval4 053 869-4 055 278 nt1 410 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 053 869-4 056 339 ntGCF_000005845::NC_000913.3::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span4 053 869-4 056 339 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 053 869 nt4 056 339 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.
PFAM architecture for RROC_0209493
Simplified PFAM architecture for RROC_0209493
PFAM domain coverage: 401 / 469 aa (85.5%)
1 aa469 aa
Response_regSigma54_activatAAA_lid_14HTH_8
- Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
- Raw architecture: Response_reg[6-115] | Sigma54_activat[140-306] | AAA_lid_14[312-395] | HTH_8[427-466]
- Domain count: 4
- Matched identifier: RROC_0209493
- Positioned domains: Response_reg 6-115 ; Response_reg 6-115 ; Sigma54_activat 140-306 ; Sigma54_activat 140-306 ; AAA_lid_14 312-395 ; AAA_lid_14 312-395 ; HTH_8 427-466 ; HTH_8 427-466
Cluster members and taxonomy
Representative gene: GCF_000005845#b3868
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key