1 PBPb#1
73-276 aa · 204 aa · 17.0% of protein
Raw token
PBPb:73:0.00000000000000432:276:209:219P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b2370
Histidine kinase, Unorthodox
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b2370Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PBPbHisKAHATPase_cResponse_regHpt
Protein length1197 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage797 / 1197 aa (66.6%)Merged over positioned domains only.
Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1197 aa
Domain-by-domain annotation6 items
2 PBPb#2
303-519 aa · 217 aa · 18.1% of protein
Raw token
PBPb:303:8.06e-40:519:224:2193 HisKA#3
711-777 aa · 67 aa · 5.6% of protein
Raw token
HisKA:711:2.14e-16:777:67:644 HATPase_c#4
825-938 aa · 114 aa · 9.5% of protein
Raw token
HATPase_c:825:1.15e-31:938:114:1095 Response_reg#5
961-1070 aa · 110 aa · 9.2% of protein
Raw token
Response_reg:961:1.25e-39:1070:110:1116 Hpt#6
1104-1188 aa · 85 aa · 7.1% of protein
Raw token
Hpt:1104:0.0000000918:1188:85:84- Raw architecture: PBPb:73:0.00000000000000432:276:209:219#PBPb:303:8.06e-40:519:224:219#HisKA:711:2.14e-16:777:67:64#HATPase_c:825:1.15e-31:938:114:109#Response_reg:961:1.25e-39:1070:110:111#Hpt:1104:0.0000000918:1188:85:84
- Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000005845::NC_000913.3::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2483755-2487967Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00022Context members
b2369b2370
Partner locus tags
b2369b2370
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_416871.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb2370Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval2 484 374-2 487 967 nt3 594 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 483 755-2 487 967 ntGCF_000005845::NC_000913.3::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span2 483 755-2 487 967 nt4 213 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 483 755 nt2 487 967 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0161002
Simplified PFAM architecture for HKOC_0161002
PFAM domain coverage: 802 / 1197 aa (67.0%)
1 aa1197 aa
SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_regHpt
- Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt
- Raw architecture: SBP_bac_3[63-276] | SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070] | Hpt[1104-1186]
- Domain count: 6
- Matched identifier: HKOC_0161002
- Positioned domains: SBP_bac_3 63-276 ; SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070 ; Hpt 1104-1186
Cluster members and taxonomy
Representative gene: GCF_000005845#b2370
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key