1 H-kinase_dim#1
166-227 aa · 62 aa · 11.1% of protein
Raw token
H-kinase_dim:166:1.29e-18:227:66:67P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b1888
Histidine kinase, CheA
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeCheALength557 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000005845#b1888Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
H-kinase_dimHATPase_cCheW
Protein length557 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage328 / 557 aa (58.9%)Merged over positioned domains only.
Domain description1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa557 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
274-411 aa · 138 aa · 24.8% of protein
Raw token
HATPase_c:274:6.96e-17:411:138:1093 CheW#3
416-543 aa · 128 aa · 23.0% of protein
Raw token
CheW:416:1.45e-29:543:134:138- Raw architecture: H-kinase_dim:166:1.29e-18:227:66:67#HATPase_c:274:6.96e-17:411:138:109#CheW:416:1.45e-29:543:134:138
- Domain description: 1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000005845::NC_000913.3::G00013
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1973360-1975324Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00013Context members
b1888
Partner locus tags
b1888
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for YP_010283911.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb1888Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval1 973 360-1 975 324 nt1 965 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 973 360-1 975 324 ntGCF_000005845::NC_000913.3::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span1 973 360-1 975 324 nt1 965 nt
Members22 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 973 360 nt1 975 324 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHpt + CheY-binding + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0886030
Simplified PFAM architecture for HKOC_0886030
PFAM domain coverage: 484 / 654 aa (74.0%)
1 aa654 aa
HptCheY-bindingH-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + CheY-binding + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[8-100] | CheY-binding[161-223] | H-kinase_dim[261-324] | HATPase_c[372-508] | CheW[514-640]
- Domain count: 5
- Matched identifier: HKOC_0886030
- Positioned domains: Hpt 8-100 ; CheY-binding 161-223 ; H-kinase_dim 261-324 ; HATPase_c 372-508 ; CheW 514-640
Cluster members and taxonomy
Representative gene: GCF_000005845#b1888
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key