Gene detail

b1222

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b1222Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1013071Run 6 · 21577 sequences · id 100% · cov 80%
External referencesNP_415740.1 · MIST4 b1222RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage314 / 598 aa (52.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
PilJ: 35-128 aa (94 aa)1HAMP: 158-225 aa (68 aa)2HisKA_3: 390-453 aa (64 aa)3HATPase_c: 496-583 aa (88 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
35-128 aa · 94 aa · 15.7% of protein
Raw tokenPilJ:35:0.00000000671:128:112:112
2 HAMP#2
158-225 aa · 68 aa · 11.4% of protein
Raw tokenHAMP:158:0.0000000000602:225:69:69
3 HisKA_3#3
390-453 aa · 64 aa · 10.7% of protein
Raw tokenHisKA_3:390:2.26e-17:453:64:68
4 HATPase_c#4
496-583 aa · 88 aa · 14.7% of protein
Raw tokenHATPase_c:496:4.83e-20:583:103:109
  • Raw architecture: PilJ:35:0.00000000671:128:112:112#HAMP:158:0.0000000000602:225:69:69#HisKA_3:390:2.26e-17:453:64:68#HATPase_c:496:4.83e-20:583:103:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1275179-1277618Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00009
Context members
b1221b1222
Partner locus tags
b1221b1222
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_415740.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb1222Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval1 275 822-1 277 618 nt1 797 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 275 179-1 277 618 ntGCF_000005845::NC_000913.3::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span1 275 179-1 277 618 nt2 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 275 179 nt1 277 618 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b1221GCF_000005845#b1221
RRNarL

1 275 179-1 275 829 nt · Reverse (-)

RefSeq NP_415739.1
b1222GCF_000005845#b1222
HKClassicCurrent focus

1 275 822-1 277 618 nt · Reverse (-)

RefSeq NP_415740.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1013071Run 6 · HK · 21577 sequences
Representative sequenceGCF_000194215#EC970246_RS08200Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1013071

Simplified PFAM architecture for HKOC_1013071

PFAM domain coverage: 301 / 608 aa (49.5%)

1 aa608 aa
PilJ: 35-129 aaPilJHAMP: 173-224 aaHAMPHisKA_3: 390-453 aaHisKA_3HATPase_c: 496-585 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[35-129] | HAMP[173-224] | HisKA_3[390-453] | HATPase_c[496-585]
  • Domain count: 4
  • Matched identifier: HKOC_1013071
  • Positioned domains: PilJ 35-129 ; HAMP 173-224 ; HisKA_3 390-453 ; HATPase_c 496-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_000194215#EC970246_RS08200

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key