Gene detail

b1129

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength486 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b1129Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1567066Run 6 · 26721 sequences · id 100% · cov 80% · representative
External referencesNP_415647.1 · MIST4 b1129RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PhoQ_SensorHAMPHisKAHATPase_c
Protein length486 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage411 / 486 aa (84.6%)Merged over positioned domains only.
Domain description1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa486 aa
PhoQ_Sensor: 10-189 aa (180 aa)1HAMP: 195-263 aa (69 aa)2HisKA: 272-330 aa (59 aa)3HATPase_c: 374-476 aa (103 aa)4
Domain-by-domain annotation4 items
1 PhoQ_Sensor#1
10-189 aa · 180 aa · 37.0% of protein
Raw tokenPhoQ_Sensor:10:1.87e-113:189:180:179
2 HAMP#2
195-263 aa · 69 aa · 14.2% of protein
Raw tokenHAMP:195:0.00000000365:263:69:69
3 HisKA#3
272-330 aa · 59 aa · 12.1% of protein
Raw tokenHisKA:272:0.000000441:330:59:64
4 HATPase_c#4
374-476 aa · 103 aa · 21.2% of protein
Raw tokenHATPase_c:374:1.29e-21:476:105:109
  • Raw architecture: PhoQ_Sensor:10:1.87e-113:189:180:179#HAMP:195:0.00000000365:263:69:69#HisKA:272:0.000000441:330:59:64#HATPase_c:374:1.29e-21:476:105:109
  • Domain description: 1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1188316-1190447Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00008
Context members
b1129b1130
Partner locus tags
b1129b1130
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_415647.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb1129Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval1 188 316-1 189 776 nt1 461 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 188 316-1 190 447 ntGCF_000005845::NC_000913.3::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span1 188 316-1 190 447 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 188 316 nt1 190 447 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b1129GCF_000005845#b1129
HKClassicCurrent focus

1 188 316-1 189 776 nt · Reverse (-)

RefSeq NP_415647.1
b1130GCF_000005845#b1130
RROmpR

1 189 776-1 190 447 nt · Reverse (-)

RefSeq NP_415648.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1567066Run 6 · HK · 26721 sequences
Representative sequenceGCF_000005845#b1129The current gene is the representative for this cluster.
PFAM architecturePhoQ_Sensor + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1567066

Simplified PFAM architecture for HKOC_1567066

PFAM domain coverage: 280 / 486 aa (57.6%)

1 aa486 aa
PhoQ_Sensor: 10-188 aaPhoQ_SensorHATPase_c: 375-475 aaHATPase_c
PhoQ_SensorHATPase_c
  • Simplified architecture: PhoQ_Sensor + HATPase_c
  • Raw architecture: PhoQ_Sensor[10-188] | HATPase_c[375-475]
  • Domain count: 2
  • Matched identifier: HKOC_1567066
  • Positioned domains: PhoQ_Sensor 10-188 ; HATPase_c 375-475
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b1129

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key