1 HAMP#1
333-407 aa · 75 aa · 8.2% of protein
Raw token
HAMP:333:0.0000000507:407:75:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b0993
Histidine kinase, Unorthodox
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeUnorthodoxLength914 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000005845#b0993Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_cResponse_regHpt
Protein length914 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage433 / 914 aa (47.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa914 aa
Domain-by-domain annotation5 items
2 HisKA#2
443-508 aa · 66 aa · 7.2% of protein
Raw token
HisKA:443:4.2e-16:508:66:643 HATPase_c#3
557-663 aa · 107 aa · 11.7% of protein
Raw token
HATPase_c:557:1.71e-34:663:108:1094 Response_reg#4
685-790 aa · 106 aa · 11.6% of protein
Raw token
Response_reg:685:0.00000000000000676:790:106:1115 Hpt#5
827-905 aa · 79 aa · 8.6% of protein
Raw token
Hpt:827:0.0000000000226:905:84:84- Raw architecture: HAMP:333:0.0000000507:407:75:69#HisKA:443:4.2e-16:508:66:64#HATPase_c:557:1.71e-34:663:108:109#Response_reg:685:0.00000000000000676:790:106:111#Hpt:827:0.0000000000226:905:84:84
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000005845::NC_000913.3::G00006
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1053434-1056178Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00006Context members
b0993
Partner locus tags
b0993
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_415513.2.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb0993Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval1 053 434-1 056 178 nt2 745 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 053 434-1 056 178 ntGCF_000005845::NC_000913.3::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span1 053 434-1 056 178 nt2 745 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 053 434 nt1 056 178 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
b0993GCF_000005845#b0993
HKUnorthodoxCurrent focus
1 053 434-1 056 178 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureTorS_sensor_domain + HAMP + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0383266
Simplified PFAM architecture for HKOC_0383266
PFAM domain coverage: 683 / 914 aa (74.7%)
1 aa914 aa
TorS_sensor_domainHAMPHisKAHATPase_cResponse_regHpt
- Simplified architecture: TorS_sensor_domain + HAMP + HisKA + HATPase_c + Response_reg + Hpt
- Raw architecture: TorS_sensor_domain[46-316] | HAMP[352-403] | HisKA[443-508] | HATPase_c[557-663] | Response_reg[685-792] | Hpt[827-905]
- Domain count: 6
- Matched identifier: HKOC_0383266
- Positioned domains: TorS_sensor_domain 46-316 ; HAMP 352-403 ; HisKA 443-508 ; HATPase_c 557-663 ; Response_reg 685-792 ; Hpt 827-905
Cluster members and taxonomy
Representative gene: GCF_000005845#b0993
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key