Gene detail

b0695

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength894 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b0695Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0408856Run 6 · 6139 sequences · id 100% · cov 80%
External referencesNP_415223.1 · MIST4 b0695RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length894 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage502 / 894 aa (56.2%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa894 aa
KdpD: 21-230 aa (210 aa)1GAF_3: 527-644 aa (118 aa)2HisKA: 664-730 aa (67 aa)3HATPase_c: 774-880 aa (107 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
21-230 aa · 210 aa · 23.5% of protein
Raw tokenKdpD:21:1.53e-142:230:210:210
2 GAF_3#2
527-644 aa · 118 aa · 13.2% of protein
Raw tokenGAF_3:527:0.00000000000424:644:130:129
3 HisKA#3
664-730 aa · 67 aa · 7.5% of protein
Raw tokenHisKA:664:0.000000000000298:730:68:64
4 HATPase_c#4
774-880 aa · 107 aa · 12.0% of protein
Raw tokenHATPase_c:774:9.31e-31:880:107:109
  • Raw architecture: KdpD:21:1.53e-142:230:210:210#GAF_3:527:0.00000000000424:644:130:129#HisKA:664:0.000000000000298:730:68:64#HATPase_c:774:9.31e-31:880:107:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span721056-724414Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00005
Context members
b0694b0695
Partner locus tags
b0694b0695
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_415223.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb0695Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval721 730-724 414 nt2 685 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span721 056-724 414 ntGCF_000005845::NC_000913.3::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span721 056-724 414 nt3 359 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
721 056 nt724 414 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b0694GCF_000005845#b0694
RROmpR

721 056-721 733 nt · Reverse (-)

RefSeq NP_415222.1
b0695GCF_000005845#b0695
HKClassicCurrent focus

721 730-724 414 nt · Reverse (-)

RefSeq NP_415223.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0408856Run 6 · HK · 6139 sequences
Representative sequenceGCF_000190835#ERDG_RS19680Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + GAF_3 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0408856

Simplified PFAM architecture for HKOC_0408856

PFAM domain coverage: 607 / 898 aa (67.6%)

1 aa898 aa
KdpD: 22-230 aaKdpDDUF4118: 403-508 aaDUF4118GAF_3: 527-644 aaGAF_3HisKA: 664-730 aaHisKAHATPase_c: 776-882 aaHATPase_c
KdpDDUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[403-508] | GAF_3[527-644] | HisKA[664-730] | HATPase_c[776-882]
  • Domain count: 5
  • Matched identifier: HKOC_0408856
  • Positioned domains: KdpD 22-230 ; DUF4118 403-508 ; GAF_3 527-644 ; HisKA 664-730 ; HATPase_c 776-882
Cluster members and taxonomy
Visualization

Representative gene: GCF_000190835#ERDG_RS19680

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key