Gene detail

b0400

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b0400Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2161283Run 6 · 6606 sequences · id 100% · cov 80% · representative
External referencesNP_414934.1 · MIST4 b0400RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
PAS: 98-194 aa (97 aa)1HisKA: 203-268 aa (66 aa)2HATPase_c: 313-424 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw tokenPAS:98:0.00000000000244:194:113:113
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw tokenHisKA:203:1.21e-19:268:66:64
3 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw tokenHATPase_c:313:1.32e-33:424:112:109
  • Raw architecture: PAS:98:0.00000000000244:194:113:113#HisKA:203:1.21e-19:268:66:64#HATPase_c:313:1.32e-33:424:112:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span417142-419184Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00001
Context members
b0399b0400
Partner locus tags
b0399b0400
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_414934.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb0400Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval417 889-419 184 nt1 296 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span417 142-419 184 ntGCF_000005845::NC_000913.3::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span417 142-419 184 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
417 142 nt419 184 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b0399GCF_000005845#b0399
RROmpR

417 142-417 831 nt · Forward (+)

RefSeq NP_414933.1
b0400GCF_000005845#b0400
HKClassicCurrent focus

417 889-419 184 nt · Forward (+)

RefSeq NP_414934.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2161283Run 6 · HK · 6606 sequences
Representative sequenceGCF_000005845#b0400The current gene is the representative for this cluster.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2161283

Simplified PFAM architecture for HKOC_2161283

PFAM domain coverage: 360 / 431 aa (83.5%)

1 aa431 aa
PhoR: 6-91 aaPhoRPAS: 99-194 aaPASHisKA: 203-268 aaHisKAHATPase_c: 313-424 aaHATPase_c
PhoRPASHisKAHATPase_c
  • Simplified architecture: PhoR + PAS + HisKA + HATPase_c
  • Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
  • Domain count: 4
  • Matched identifier: HKOC_2161283
  • Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b0400

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 6 606 total members. Page 1 / 133.

GCF_000005845#b0400 (representative)
b0400 · HK · Classic
RefSeq: NP_414934.1
GCF_000010245#Y75_RS02055
Y75_RS02055 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000019425#ECDH10B_RS01830
ECDH10B_RS01830 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000022345#BWG_RS01600
BWG_RS01600 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000023365#ECDH1_RS17080
ECDH1_RS17080 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000146735#TAGB_RS01985
TAGB_RS01985 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000158415#ESBG_RS18380
ESBG_RS18380 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000159895#ESCG_RS18295
ESCG_RS18295 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000164235#HMPREF9540_RS13670
HMPREF9540_RS13670 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000164275#HMPREF9543_RS05120
HMPREF9543_RS05120 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000164475#HMPREF9541_RS15915
HMPREF9541_RS15915 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000164515#HMPREF9547_RS05630
HMPREF9547_RS05630 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000164555#HMPREF9551_RS12030
HMPREF9551_RS12030 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000166535#TW10598_RS03995
TW10598_RS03995 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000176535#ECHG_RS19070
ECHG_RS19070 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000184765#EC3431_RS08990
EC3431_RS08990 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000190815#ERCG_RS21640
ERCG_RS21640 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000190835#ERDG_RS20970
ERDG_RS20970 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000194395#EC50959_RS14095
EC50959_RS14095 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000194535#EC23916_RS07395
EC23916_RS07395 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000194555#EC24168_RS20855
EC24168_RS20855 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000194645#EC32303_RS20490
EC32303_RS20490 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000194705#ECB41_RS05075
ECB41_RS05075 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000220005#UMNF18_RS24230
UMNF18_RS24230 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000224395#IAM_RS13055
IAM_RS13055 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000225145#ECSTECEH250_RS21210
ECSTECEH250_RS21210 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000225225#BC61_RS20045
BC61_RS20045 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000234275#KES_RS0101025
KES_RS0101025 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000249675#BB92_RS21110
BB92_RS21110 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000249715#ECDEC7B_RS21470
ECDEC7B_RS21470 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000258865#OQE_RS04815
OQE_RS04815 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000259425#UWO_RS08075
UWO_RS08075 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000261145#ESMG_RS20025
ESMG_RS20025 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000264155#EC75_RS03560
EC75_RS03560 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000269645#COA_RS0100990
COA_RS0100990 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000270105#ECDH1ME8569_RS02065
ECDH1ME8569_RS02065 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000273425#AYT25_RS02055
AYT25_RS02055 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000304075#BD75_RS20365
BD75_RS20365 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000304115#BD92_RS20505
BD92_RS20505 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000304255#ECAD30_RS12755
ECAD30_RS12755 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000305175#BE82_RS19475
BE82_RS19475 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000305355#BC17_RS19675
BC17_RS19675 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000326825#WGQ_RS19470
WGQ_RS19470 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000326925#WII_RS14675
WII_RS14675 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000333175#ECK5_RS22235
ECK5_RS22235 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000340255#C201_RS20095
C201_RS20095 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000350025#C4893_RS20620
C4893_RS20620 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000350685#WCM_RS12315
WCM_RS12315 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000350885#WGI_RS19860
WGI_RS19860 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12
GCF_000351165#A15Y_RS19355
A15Y_RS19355 · HK · Classic
RefSeq: WP_000893623.1
UniProt: A0AAP9SJ12

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key