Gene detail

b0400

Histidine kinase, Classic

Escherichia coli str. K-12 substr. MG1655 · GCF_000005845

ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b0400Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2161283Run 6 · 6606 sequences · id 100% · cov 80% · representative
External referencesNP_414934.1 · MIST4 b0400RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
PAS: 98-194 aa (97 aa)1HisKA: 203-268 aa (66 aa)2HATPase_c: 313-424 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw tokenPAS:98:0.00000000000244:194:113:113
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw tokenHisKA:203:1.21e-19:268:66:64
3 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw tokenHATPase_c:313:1.32e-33:424:112:109
  • Raw architecture: PAS:98:0.00000000000244:194:113:113#HisKA:203:1.21e-19:268:66:64#HATPase_c:313:1.32e-33:424:112:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000005845::NC_000913.3::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span417142-419184Genomic interval covered by the local TCS group.
Context group IDGCF_000005845::NC_000913.3::G00001
Context members
b0399b0400
Partner locus tags
b0399b0400
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_414934.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagb0400Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval417 889-419 184 nt1 296 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span417 142-419 184 ntGCF_000005845::NC_000913.3::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000005845::NC_000913.3::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span417 142-419 184 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
417 142 nt419 184 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

b0399GCF_000005845#b0399
RROmpR

417 142-417 831 nt · Forward (+)

RefSeq NP_414933.1
b0400GCF_000005845#b0400
HKClassicCurrent focus

417 889-419 184 nt · Forward (+)

RefSeq NP_414934.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2161283Run 6 · HK · 6606 sequences
Representative sequenceGCF_000005845#b0400The current gene is the representative for this cluster.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2161283

Simplified PFAM architecture for HKOC_2161283

PFAM domain coverage: 360 / 431 aa (83.5%)

1 aa431 aa
PhoR: 6-91 aaPhoRPAS: 99-194 aaPASHisKA: 203-268 aaHisKAHATPase_c: 313-424 aaHATPase_c
PhoRPASHisKAHATPase_c
  • Simplified architecture: PhoR + PAS + HisKA + HATPase_c
  • Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
  • Domain count: 4
  • Matched identifier: HKOC_2161283
  • Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b0400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key