CEA/DSV/IBeB/SBVMe/LEMIRE

Gene name	P2CS description	Original description
Acidobacterium capsulatum ATCC 51196 ACP_2711 (GI 225874272)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	pyridine nucleotide-disulfide oxidoreductase
Actinoplanes friuliensis DSM 7358 AFR_33225 (GI 556569531)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	putative thioredoxin reductase
Actinoplanes missouriensis 431 AMIS_66030 (GI 383781772)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	putative thioredoxin reductase
Actinoplanes sp. SE50/110 ACPL_6856 (GI 386851793)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Actinoplanes sp. N902-109 L083_6438 (GI 494688854)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Amycolatopsis mediterranei S699 RAM_07470 (GI 384146627)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Amycolatopsis mediterranei RB B737_1463 (GI 532458143)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Amycolatopsis mediterranei S699 AMES_1462 (GI 399535281)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Amycolatopsis mediterranei U32 AMED_1472 (GI 300783396)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Amycolatopsis orientalis HCCB10007 AORI_1568 (GI 506930121)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase (NADPH)
Anabaena cylindrica PCC 7122 Anacy_4396 (GI 440683871)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver protein
Burkholderia phymatum STM815 Bphy_4576 (GI 186473391)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Burkholderia sp. YI23 BYI23_C009390 (GI 377808331)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Catenulispora acidiphila DSM 44928 Caci_6387 (GI 256395518)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Cellulomonas fimi ATCC 484 Celf_3436 (GI 332671927)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver protein
Chitinophaga pinensis DSM 2588 Cpin_1342 (GI 256420388)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Chroococcidiopsis thermalis PCC 7203 Chro_1451 (GI 428206492)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Chroococcidiopsis thermalis PCC 7203 Chro_2181 (GI 428207199)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Conexibacter woesei DSM 14684 Cwoe_1190 (GI 284042654)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Cyanothece sp. PCC 7822 plasmid Cy782201 Cyan7822_6003 (GI 307592325)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Desulfobacterium autotrophicum HRM2 HRM2_22750 (GI 224369370)	Response regulator, TrxB family 2 Pyr_redox,2 Fer4,1 Response_reg Genomic Context	protein HdrA4
Desulfovibrio aespoeensis Aspo-2 Daes_0782 (GI 317152497)	Response regulator, TrxB family 1 Pyr_redox,3 Fer4,1 Response_reg Genomic Context	response regulator receiver
Desulfovibrio africanus str. Walvis Bay Desaf_1863 (GI 374300214)	Response regulator, TrxB family 2 Pyr_redox,4 Fer4,1 Response_reg Genomic Context	response regulator receiver protein
Desulfomicrobium baculatum DSM 4028 Dbac_2345 (GI 256830113)	Response regulator, TrxB family 1 Pyr_redox,4 Fer4,1 Response_reg Genomic Context	response regulator receiver protein
Desulfovibrio desulfuricans ND132 DND132_1389 (GI 376296172)	Response regulator, TrxB family 2 Pyr_redox,4 Fer4,1 Response_reg Genomic Context	response regulator receiver modulated heterodisulfide reductase subunit A
Desulfohalobium retbaense DSM 5692 Dret_0418 (GI 258404551)	Response regulator, TrxB family 4 Fer4,1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Desulfobacula toluolica Tol2 TOL2_C17900 (GI 408419241)	Response regulator, TrxB family 2 Pyr_redox,3 Fer4,1 Response_reg Genomic Context	heterodisulfide reductase-like protein, iron-sulfur subunit HdlA5
Dyadobacter fermentans DSM 18053 Dfer_0369 (GI 255034182)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Fibrella aestuarina BUZ 2 FAES_1017 (GI 436834405)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Frankia alni ACN14a FRAAL1961 (GI 111221399)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Frankia sp. EuI1c FraEuI1c_2508 (GI 312196351)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Frankia sp. EuI1c FraEuI1c_5935 (GI 312199728)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Geodermatophilus obscurus DSM 43160 Gobs_2253 (GI 284990752)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Gloeobacter kilaueensis JS1 GKIL_2947 (GI 554637256)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Gloeobacter violaceus PCC 7421 glr0480 (GI 37520049)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Granulicella mallensis MP5ACTX8 AciX8_3022 (GI 374311925)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Granulicella tundricola AciX9_1187 (GI 322434818)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Haliscomenobacter hydrossis DSM 1100 Halhy_2582 (GI 332664537)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Intrasporangium calvum DSM 43043 Intca_2808 (GI 317125924)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Kineococcus radiotolerans SRS30216 Krad_0457 (GI 152964427)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Kineococcus radiotolerans SRS30216 Krad_2298 (GI 152966259)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Kribbella flavida DSM 17836 Kfla_5282 (GI 284033164)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Modestobacter marinus MODMU_2052 (GI 389863734)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	two component thioredoxin reductase carring response regulator
Modestobacter marinus MODMU_4032 (GI 389865668)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	two-component response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium chubuense NBB4 Mycch_0995 (GI 392414879)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Mycobacterium gilvum PYR-GCK Mflv_5003 (GI 145225579)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium intracellulare MOTT-64 OCQ_44050 (GI 379763841)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	FAD-dependent pyridine nucleotide-disulfide oxidoreductase protein
Mycobacterium indicus pranii MTCC 9506 MIP_06449 (GI 406032533)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase 1
Mycobacterium intracellulare ATCC 13950 OCU_42700 (GI 379748989)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium intracellulare MOTT-02 OCO_42930 (GI 379756305)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium neoaurum VKM Ac-1815D D174_07020 (GI 565985124)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	chemotaxis protein CheY
Mycobacterium sp. MOTT36Y W7S_21440 (GI 387877660)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	FAD-dependent pyridine nucleotide-disulfide oxidoreductase protein
Mycobacterium smegmatis JS623 Mycsm_01073 (GI 433645901)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Mycobacterium smegmatis str. MC2 155 MSMEI_1480 (GI 399985900)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium sp. JLS Mjls_1097 (GI 126433704)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium sp. KMS Mkms_1086 (GI 119867138)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium sp. MCS Mmcs_1070 (GI 108798043)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium smegmatis str. MC2 155 MSMEG_1516 (GI 118470493)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Mycobacterium sp. Spyr1 Mspyr1_44210 (GI 315445932)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Mycobacterium vanbaalenii PYR-1 Mvan_1371 (GI 120402382)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Mycobacterium yongonense 05-1390 OEM_43160 (GI 523915756)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	FAD-dependent pyridine nucleotide-disulfide oxidoreductase protein
Myxococcus stipitatus DSM 14675 MYSTI_07288 (GI 442324223)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin-disulfide reductase
Nakamurella multipartita DSM 44233 Namu_4588 (GI 258654700)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Nocardia brasiliensis ATCC 700358 O3I_039620 (GI 407649086)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	putative thioredoxin reductase
Nocardia cyriacigeorgica GUH-2 NOCYR_5110 (GI 379711285)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	putative thioredoxin reductase
Nocardia farcinica IFM 10152 nfa52850 (GI 54027259)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Nonlabens dokdonensis DSW-6 DDD_2233 (GI 443244156)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase carring response regulator receiver domain protein
Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133) Npun_R0589 (GI 186681097)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase
Pseudonocardia dioxanivorans CB1190 Psed_4017 (GI 331697797)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD-dependent pyridine nucleotide-disulfide oxidoreductase
Pseudanabaena sp. PCC 7367 Pse7367_1900 (GI 428218139)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver protein
Rhodococcus erythropolis PR4 RER_40230 (GI 226307510)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	two-component system thioredoxin reductase
Rhodococcus erythropolis CCM2595 O5Y_18675 (GI 532365888)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	two-component system thioredoxin reductase
Rhodococcus jostii RHA1 RHA1_ro04004 (GI 111020987)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator/ thioredoxin-disulfide reductase
Rhodococcus opacus B4 ROP_38820 (GI 226363292)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	two-component system thioredoxin reductase
Rivularia sp. PCC 7116 Riv7116_6495 (GI 427739827)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Simiduia agarivorans SA1 = DSM 21679 M5M_15220 (GI 410665535)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	rubredoxin--NAD(+) reductase
Sphaerobacter thermophilus DSM 20745 Sthe_0596 (GI 269836627)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Spirosoma linguale DSM 74 Slin_6098 (GI 284040929)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase
Streptomyces bingchenggensis BCW-1 SBI_01926 (GI 374984683)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces collinus Tu 365 B446_04305 (GI 529223679)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces coelicolor A3(2) SCO7298 (GI 21225574)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces davawensis JCM 4913 BN159_8285 (GI 471327760)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces fulvissimus DSM 40593 SFUL_869 (GI 488608401)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	Thioredoxin reductase
Streptomyces hygroscopicus subsp. jinggangensis TL01 SHJGH_1894 (GI 474980428)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces hygroscopicus subsp. jinggangensis 5008 SHJG_2129 (GI 386838219)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptosporangium roseum DSM 43021 Sros_2038 (GI 271963570)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	pyridine nucleotide-disulfide oxidoreductase
Streptomyces scabiei 87.22 SCAB_62661 (GI 290960640)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Streptomyces scabiei 87.22 SCAB_8001 (GI 290955374)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Syntrophobacter fumaroxidans MPOB Sfum_0821 (GI 116748266)	Response regulator, TrxB family 2 Pyr_redox,3 Fer4,1 Response_reg Genomic Context	hypothetical protein
Synechococcus sp. PCC 7502 Syn7502_03180 (GI 428223029)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	thioredoxin reductase
Terriglobus roseus DSM 18391 Terro_3388 (GI 390959181)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	thioredoxin reductase
Terriglobus saanensis SP1PR4 AciPR4_0962 (GI 320106199)	Response regulator, TrxB family 1 Response_reg,1 Pyr_redox Genomic Context	response regulator receiver protein
Tsukamurella paurometabola DSM 20162 Tpau_0406 (GI 296138143)	Response regulator, TrxB family 1 Response_reg,2 Pyr_redox Genomic Context	response regulator receiver modulated FAD- dependent pyridine nucleotide-disulfide oxidoreductase